ID A0A0B5DUM7_9ACTN Unreviewed; 494 AA.
AC A0A0B5DUM7;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:AJE44401.1, ECO:0000313|EMBL:MBB4796041.1};
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:QEV42888.1};
GN ORFNames=BJY54_006653 {ECO:0000313|EMBL:MBB4796041.1}, CP978_33995
GN {ECO:0000313|EMBL:QEV42888.1}, SNOD_33760
GN {ECO:0000313|EMBL:AJE44401.1};
OS Streptomyces nodosus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=40318 {ECO:0000313|EMBL:AJE44401.1, ECO:0000313|Proteomes:UP000031526};
RN [1] {ECO:0000313|Proteomes:UP000031526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|Proteomes:UP000031526};
RA Sweeney P., Stephens N., Murphy C., Caffrey P.;
RT "Sequence of the Streptomyces nodosus genome.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AJE44401.1, ECO:0000313|Proteomes:UP000031526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|EMBL:AJE44401.1,
RC ECO:0000313|Proteomes:UP000031526};
RX PubMed=26497174;
RA Sweeney P., Murphy C.D., Caffrey P.;
RT "Exploiting the genome sequence of Streptomyces nodosus for enhanced
RT antibiotic production.";
RL Appl. Microbiol. Biotechnol. 100:1285-1295(2016).
RN [3] {ECO:0000313|EMBL:QEV42888.1, ECO:0000313|Proteomes:UP000325763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|EMBL:QEV42888.1,
RC ECO:0000313|Proteomes:UP000325763};
RA Lee N., Cho B.-K.;
RT "Streptomyces genome completion.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:MBB4796041.1, ECO:0000313|Proteomes:UP000544950}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40109 {ECO:0000313|EMBL:MBB4796041.1,
RC ECO:0000313|Proteomes:UP000544950};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; CP009313; AJE44401.1; -; Genomic_DNA.
DR EMBL; JACHMR010000001; MBB4796041.1; -; Genomic_DNA.
DR EMBL; CP023747; QEV42888.1; -; Genomic_DNA.
DR RefSeq; WP_043447530.1; NZ_JACHMR010000001.1.
DR STRING; 40318.SNOD_33760; -.
DR KEGG; snq:CP978_33995; -.
DR HOGENOM; CLU_009289_1_0_11; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000031526; Chromosome.
DR Proteomes; UP000325763; Chromosome.
DR Proteomes; UP000544950; Unassembled WGS sequence.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:MBB4796041.1};
KW Cell division {ECO:0000313|EMBL:MBB4796041.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000031526}.
FT DOMAIN 159..490
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 494 AA; 52398 MW; 9EECDD96A14B4180 CRC64;
MNRPLRAIAV FCGLLMLALL IRANWLQYGV ADELASDANN RRVQIERFAS PRGDIIVGGQ
AVTGSEAVAG RELKYKRSYV NGPMYAPVTG FASQAQGMSL LEKTYDGILS GQDDRLAFQH
FLNVVTGKDR GTGAVVTTID PRAQKAAYEG LTGLKGARGA VVALDPKTGK VLALASAPSY
DPSVFAGNTF KESDKFLALD KDKRKPLANR PLRETYPPGS TFKILTAAAA LEHGVVTDID
APSGAVSPYP LPQSTNRIGS EAGDAVCGNA SMKTAMQYSC NNVFLDAAAK LGQDRMRETA
EKFGFNEDVY SPDFGDLLAT KSIYPQDLDK PGTALTGMGQ GSLTSTPMQM AVVTAALAND
GTLMQPYIVD EIRAPDLSTL EKTKPAVMSQ AVSADTARKV QQMMEHTAKE GSAQRALIDG
IIVGGKTGTA QRGVNVADEV PYGWFVSYGK KPDGASVAVA VFIDPTDMDI SRQDISGGRL
GAPIARSVMK AVLQ
//
