ID A0A0B5EJ05_STRA4 Unreviewed; 595 AA.
AC A0A0B5EJ05;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=cellulose synthase (UDP-forming) {ECO:0000256|ARBA:ARBA00012539};
DE EC=2.4.1.12 {ECO:0000256|ARBA:ARBA00012539};
GN ORFNames=SLNWT_1877 {ECO:0000313|EMBL:AJE82253.1};
OS Streptomyces albus (strain ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 /
OS NBRC 107858).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1081613 {ECO:0000313|EMBL:AJE82253.1, ECO:0000313|Proteomes:UP000031523};
RN [1] {ECO:0000313|EMBL:AJE82253.1, ECO:0000313|Proteomes:UP000031523}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 / NBRC 107858
RC {ECO:0000313|Proteomes:UP000031523};
RA Lu C.;
RT "Enhanced salinomycin production by adjusting the supply of polyketide
RT extender units in Streptomyce albus DSM 41398.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP010519; AJE82253.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B5EJ05; -.
DR KEGG; sals:SLNWT_1877; -.
DR Proteomes; UP000031523; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd06421; CESA_CelA_like; 1.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43867; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR PANTHER; PTHR43867:SF2; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Cellulose biosynthesis {ECO:0000256|ARBA:ARBA00022916};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000031523};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AJE82253.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 41..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 505..523
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 529..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 221..427
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF13632"
FT REGION 562..595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 595 AA; 65497 MW; 2A662AB923A7D2B1 CRC64;
MPPEGYDYES YSRLAGPLTQ PTGRPYRVRY RSLLSTEPRR LRAVALMTLA PILTAVLLVY
LVWPSHWTRR EGGAAWLVGL DITMLAAIGL IETFMLVNVV SIAHATMVAR DPVPVVPQPG
TRVAFLTTFV PGRESLAMLR GTLEGAVRVR HTGPLDVWLL DEGDDAQAKA LCAELGVRHF
TRHGVPEWNR ESGAHKARTK HGNYNAWLAL HGGDYEFFAS VDTDHVPVPD FLERMMGYFR
DPDVAFVVGP QVYGNYLTPV TKAAESQQFL FHALIQRAGN RYRSAMFVGT NNVVRIAALR
QIGGLRDSIT EDMATGFELH RQRNPLTGRH WESVYTPDVL AVGEGPASWT DFFTQQTRWS
RGTYETLLKQ YRKAPLSMPG GRLFSYSLML AYYPMAAVNW LLGVLSCVLF LWFGASGTQV
AASVWLMLYS DAAALQIGLY LWNRRHNVSP HEPQGSGGLA GMAMSAVSAP IYAKSLAEAV
LRRPSRFVVT PKGDVSPDRL LTFRIHLLWA GVLIASLTAS ALLDHTHAAM RTWAALATCI
SLAPATVWAC GEYRRRRAVR AEGRARVPEP ETAPALARPV SSASAPVSTS TSGGN
//
