ID A0A0B5EWC0_STRA4 Unreviewed; 865 AA.
AC A0A0B5EWC0;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Putative integral membrane sensor protein {ECO:0000313|EMBL:AJE87128.1};
GN ORFNames=SLNWT_6752 {ECO:0000313|EMBL:AJE87128.1};
OS Streptomyces albus (strain ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 /
OS NBRC 107858).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1081613 {ECO:0000313|EMBL:AJE87128.1, ECO:0000313|Proteomes:UP000031523};
RN [1] {ECO:0000313|EMBL:AJE87128.1, ECO:0000313|Proteomes:UP000031523}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 / NBRC 107858
RC {ECO:0000313|Proteomes:UP000031523};
RA Lu C.;
RT "Enhanced salinomycin production by adjusting the supply of polyketide
RT extender units in Streptomyce albus DSM 41398.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP010519; AJE87128.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B5EWC0; -.
DR KEGG; sals:SLNWT_6752; -.
DR Proteomes; UP000031523; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16936; HATPase_RsbW-like; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR033463; sCache_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF13581; HATPase_c_2; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF17203; sCache_3_2; 1.
DR Pfam; PF07228; SpoIIE; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00091; PAS; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000031523};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 159..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 199..240
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
SQ SEQUENCE 865 AA; 92511 MW; 2EEEAA239F9B5EE7 CRC64;
MFVLQALIVL VLVVVAVVAM LIQARDDRFQ AARDRSLAAA EAFAHSPGLV ETLRGPDPSA
QLQPRTEAAR MLGGVDFIVV MNREGIRYTH PRPELIGKRF VGTIEPSLSG RITVERVSGP
LGQEVQVVVP VTDARGKIVA LVSAGVRVSE VSSAFERQLP VVLGVSAAAL VLATAGTALV
TRRLRRQTHG LGPSEMTRMY EHHDAVLHSV REGVLIVSGD GRVLLANDEA RRLLGLPKDS
EGARVADLGL DPRIAELLAS RRAATDEVVP VQDLLLAVNN RPTDRAGGPP GSVATLRDST
ELRALAGKAE AAQGRLRLLY EASVRVGTTL DVQRTADELT QVSVPGFADT ATVDLAEAVL
RGEEPRPVTG QEAPQLRRIS LTGAHGTHPL YRPGDLVTFA APTPQATGFT GGEPVLVRDM
RTSDGWRTQG AERSQDVLDH GYRSMITVPL KARGVLMGIV NYWRTEEGEP FEEEDLSLAE
ELAARAAVCI DNARRFTREH EMAVTLQRSL LPRALPEQNA LDIAYRYLPA QSGVGGDWFD
VIPLPGARVA LVVGDVVGHG MHAAATMGRL RTAVQNFSSL DLPPDELLGH LDELIARIDQ
ENTAAGTEAA LAGATCVYAI YDPASGLCQL ARAGHPMPAV VRPDGSVDFP DIPVGPPLGV
GNLPFEAAEL HLPEGSSLVL YTDGLIEDRS RDIDVGMEML RAALSRPGLS PEDSCEAVLR
ALLPARPGDD IALLVARTRV LAADQAVSWQ VPPEPAAVAG ARAELARHLV DWGLGDAVFT
AELILSELIT NGIRYASGPI GIRLLRDRSL ICEVSDTSST SPHLRSAAAE DEGGRGLFLI
SQLAERWGTR YTPEGKVIWA ELPLS
//
