ID A0A0B5EYA2_STRA4 Unreviewed; 1273 AA.
AC A0A0B5EYA2;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=SLNWT_3904 {ECO:0000313|EMBL:AJE84280.1};
OS Streptomyces albus (strain ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 /
OS NBRC 107858).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1081613 {ECO:0000313|EMBL:AJE84280.1, ECO:0000313|Proteomes:UP000031523};
RN [1] {ECO:0000313|EMBL:AJE84280.1, ECO:0000313|Proteomes:UP000031523}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 / NBRC 107858
RC {ECO:0000313|Proteomes:UP000031523};
RA Lu C.;
RT "Enhanced salinomycin production by adjusting the supply of polyketide
RT extender units in Streptomyce albus DSM 41398.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP010519; AJE84280.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B5EYA2; -.
DR KEGG; sals:SLNWT_3904; -.
DR Proteomes; UP000031523; Chromosome.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR001466; Beta-lactam-related.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00144; Beta-lactamase; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000031523}.
FT DOMAIN 739..814
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 70..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..41
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..98
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1273 AA; 134701 MW; 381BF2CBFEE2988D CRC64;
MGDPSAASSA VTVQLPLREP RGTTPEPSRH TWSERHPGEI RRCAEEAGAR ADDLAHAAFA
HLLHRYSGQH PTLGRSADPA PDARPGTPPA EYAVPPAPDD RVPLPVAAAA LARQRAAQAP
RTGEPAVLGA GLRAGSHLRR PGIPLPTGYD LLLEIVTEGA ATALVLHHDA ALLSEALVAR
MAVNLGVLLT GAVARPGAAT GDLDVLSAAE SHRLLTELND TAHPYDTAAT VHGLVEAQAA
RTPAAPAVAC GGTVWSYREL DERANRLARA LAARGIAPGA RIGVSLGRSH RTVALLLAVH
KAGCAYVPLD PAYPAERLRA VAATAGMSLV VHEGERSPEW LAETGVPGLP AGELGEKAAA
EEASAPRVDV APADTTHLIH TSGSTGLPKG VVISHRNVVA LLAWAEDTYP AEDLARVLFS
TSLNFDLSVF ELWAPLTRGG CVVVVENVLA LTEDPGLAPT LVNTVPSALN VLLRREAVPA
SVRVLNVAGE PLPRELVQEA FARTSAERLY NLYGPSEDTT YSTWKCFTGP TTGPVTIGVP
VHNTRAHLLD ERGRPVPLGA VGELHLGGDG VADGYFGDPV RTAAAFLPAP ARPEPGGPDC
RLYRTGDLAR WTEDGELRFL GRRDNQVKVR GFRIELGEIE SVLREAVGLR EVAALAVPAA
DGTRLVCWIG SGAQACPTEE VAAHLRAKLP HYMQPARILC LESLPLLPNG KVDRKALAAR
PVDWGGTGAT APDGSAALTG SGPEEREVAA AWTELLGLPQ LSAELDFFSV GGHSLLANLL
AARLGDTAGR PVRVAEIYAH RTLAAQAELL RRKRAETPAA SGTAGGPGRA AAVAATLRES
ARAHGVPGAG VAVLLDGEVE FTYHGIADMA AGTPYGPGTR QRITCITKPM LAFVALRLVD
RGLLGLDEPL DGILPEAFVR RGGERVRVTL RQLLSHTSGV DDSYEVWHDT DLPDLDGYLA
TLGEYGQLFS PGEVFAYSAV GTSIVAGIIE KLLGMPWRRA VNELLLLPLG IAAVPETLAE
NGHYGDAVST GYLWHEPTKS YRPHDPPRQT VADDAAGSFS VCLTLEELSR IARLALDDGL
APSGERLLSA ALAAEMRTPQ IPVPGHHFMH AWGLGWLMFG PSAFGFNSNG SGHHNFVQIF
PEERSFLLLL ANAYPAFGLY EDLLREVTGE GLIRTGRPFE MALGDCPGVY ASDGYRLHVL
PGEEHLRYEY AERAPDGTWR PLDEGSLVLS GAGGFSSMSE RNVLAGSISF IPAPGTSTPG
YVRIGQRFAR RTR
//
