ID A0A0B5HNA9_9ACTN Unreviewed; 522 AA.
AC A0A0B5HNA9;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 {ECO:0000256|ARBA:ARBA00040298};
GN ORFNames=SVTN_03040 {ECO:0000313|EMBL:AJF63605.1};
OS Streptomyces vietnamensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=362257 {ECO:0000313|EMBL:AJF63605.1, ECO:0000313|Proteomes:UP000031774};
RN [1] {ECO:0000313|EMBL:AJF63605.1, ECO:0000313|Proteomes:UP000031774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GIMV4.0001 {ECO:0000313|Proteomes:UP000031774};
RA Deng M.R., Guo J., Ma L.Y., Feng G.D., Mo C.Y., Zhu H.H.;
RT "Complete genome sequence of Streptomyces vietnamensis strain GIMV4.0001, a
RT genetic manipulable producer of the benzoisochromanequinone antibiotic
RT granaticin.";
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable oxidoreductase that may play a role as regulator of
CC mitochondrial function. {ECO:0000256|ARBA:ARBA00037217}.
CC -!- SUBUNIT: Interacts with COX5B; this interaction may contribute to
CC localize PYROXD2 to the inner face of the inner mitochondrial membrane.
CC {ECO:0000256|ARBA:ARBA00038825}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix
CC {ECO:0000256|ARBA:ARBA00004305}.
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DR EMBL; CP010407; AJF63605.1; -; Genomic_DNA.
DR RefSeq; WP_041127689.1; NZ_CP010407.1.
DR AlphaFoldDB; A0A0B5HNA9; -.
DR STRING; 362257.SVTN_03040; -.
DR KEGG; svt:SVTN_03040; -.
DR HOGENOM; CLU_019327_0_1_11; -.
DR Proteomes; UP000031774; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR10668; PHYTOENE DEHYDROGENASE; 1.
DR PANTHER; PTHR10668:SF103; PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF01593; Amino_oxidase; 1.
DR Pfam; PF13450; NAD_binding_8; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000031774}.
FT DOMAIN 153..313
FT /note="Amine oxidase"
FT /evidence="ECO:0000259|Pfam:PF01593"
SQ SEQUENCE 522 AA; 54843 MW; C368D6C0F61F332B CRC64;
MTDRDPLPDA PAPTSSYDAV VVGGGHNGLV AAAYLARAGR SVLVLERLGS TGGAAVSTRP
FAGVDARLSR YSYLVSLLPE KIVRELGLRF AVRKRSISSY TPKGDGGLLV GGGPDRTRAS
FAALTGSDSA YEAWQAFYGR TGEAARRIFP TLTEPLPTRA ELRARVDDAD TWRMLFEEPL
GVTVEKTFAD DLVRGVVLTD ALIGTFADAH DPALLQNRCF LYHVIGGGTG DWDVPVGGMG
ALTDALAGAA RAAGARILTG HEATRIETDG RRASITYRTA DGEGTVEAGQ VLVNASPQEL
AALLGETPPP APEGAQLKVN MLLTRLPRLR DRSVDPREAF AGTFHIAEGY GQLATAHAEA
AAGRLPSAPP SEIYCHSLTD PTILGPELAA TGHQTLTLFG LHTPARLFAA DNEGTRAKLL
AATLAQLDAH LDEPIADCLA LDAEGRPCIE AKTPLDLERE LRLPGGHIFH RDLSFPYGEE
GTGRWGVETP HANVLLCGAG AIRGGGVSGI PGHNAAMAAL GR
//
