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Database: UniProt
Entry: A0A0B5HTZ5_9ACTN
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ID   A0A0B5HTZ5_9ACTN        Unreviewed;       100 AA.
AC   A0A0B5HTZ5;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   24-JAN-2024, entry version 45.
DE   RecName: Full=Urease subunit gamma {ECO:0000256|HAMAP-Rule:MF_00739, ECO:0000256|RuleBase:RU003850};
DE            EC=3.5.1.5 {ECO:0000256|HAMAP-Rule:MF_00739, ECO:0000256|RuleBase:RU003850};
DE   AltName: Full=Urea amidohydrolase subunit gamma {ECO:0000256|HAMAP-Rule:MF_00739};
GN   Name=ureA {ECO:0000256|HAMAP-Rule:MF_00739,
GN   ECO:0000313|EMBL:AJF63966.1};
GN   ORFNames=SVTN_05580 {ECO:0000313|EMBL:AJF63966.1};
OS   Streptomyces vietnamensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=362257 {ECO:0000313|EMBL:AJF63966.1, ECO:0000313|Proteomes:UP000031774};
RN   [1] {ECO:0000313|EMBL:AJF63966.1, ECO:0000313|Proteomes:UP000031774}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GIMV4.0001 {ECO:0000313|Proteomes:UP000031774};
RA   Deng M.R., Guo J., Ma L.Y., Feng G.D., Mo C.Y., Zhu H.H.;
RT   "Complete genome sequence of Streptomyces vietnamensis strain GIMV4.0001, a
RT   genetic manipulable producer of the benzoisochromanequinone antibiotic
RT   granaticin.";
RL   Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+); Xref=Rhea:RHEA:20557,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16199,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:28938; EC=3.5.1.5;
CC         Evidence={ECO:0000256|ARBA:ARBA00000242, ECO:0000256|HAMAP-
CC         Rule:MF_00739, ECO:0000256|RuleBase:RU003850};
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3) from
CC       urea (urease route): step 1/1. {ECO:0000256|HAMAP-Rule:MF_00739}.
CC   -!- SUBUNIT: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha)
CC       subunits. Three heterotrimers associate to form the active enzyme.
CC       {ECO:0000256|HAMAP-Rule:MF_00739}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00739,
CC       ECO:0000256|RuleBase:RU003850}.
CC   -!- SIMILARITY: Belongs to the urease gamma subunit family.
CC       {ECO:0000256|HAMAP-Rule:MF_00739, ECO:0000256|RuleBase:RU003850}.
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DR   EMBL; CP010407; AJF63966.1; -; Genomic_DNA.
DR   RefSeq; WP_041128049.1; NZ_CP010407.1.
DR   AlphaFoldDB; A0A0B5HTZ5; -.
DR   STRING; 362257.SVTN_05580; -.
DR   KEGG; svt:SVTN_05580; -.
DR   HOGENOM; CLU_145825_1_0_11; -.
DR   UniPathway; UPA00258; UER00370.
DR   Proteomes; UP000031774; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00390; Urease_gamma; 1.
DR   Gene3D; 3.30.280.10; Urease, gamma-like subunit; 1.
DR   HAMAP; MF_00739; Urease_gamma; 1.
DR   InterPro; IPR012010; Urease_gamma.
DR   InterPro; IPR002026; Urease_gamma/gamma-beta_su.
DR   InterPro; IPR036463; Urease_gamma_sf.
DR   NCBIfam; TIGR00193; urease_gam; 1.
DR   PANTHER; PTHR33569; UREASE; 1.
DR   PANTHER; PTHR33569:SF1; UREASE; 1.
DR   Pfam; PF00547; Urease_gamma; 1.
DR   PIRSF; PIRSF001223; Urease_gamma; 1.
DR   SUPFAM; SSF54111; Urease, gamma-subunit; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00739};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00739};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031774}.
SQ   SEQUENCE   100 AA;  11077 MW;  05968CB65FECB0FE CRC64;
     MQLSPHEQER LLIHVAADVA EKRRARGVRL NHPEAVALIT SHILEGARDG RTVAELMASG
     RKVLTRDEVM DGIPEMIHDV QVEATFPDGT KLVTVHDPII
//
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