ID A0A0B5IKX6_9ACTN Unreviewed; 337 AA.
AC A0A0B5IKX6;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:AJF69039.1};
GN ORFNames=SVTN_36845 {ECO:0000313|EMBL:AJF69039.1};
OS Streptomyces vietnamensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=362257 {ECO:0000313|EMBL:AJF69039.1, ECO:0000313|Proteomes:UP000031774};
RN [1] {ECO:0000313|EMBL:AJF69039.1, ECO:0000313|Proteomes:UP000031774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GIMV4.0001 {ECO:0000313|Proteomes:UP000031774};
RA Deng M.R., Guo J., Ma L.Y., Feng G.D., Mo C.Y., Zhu H.H.;
RT "Complete genome sequence of Streptomyces vietnamensis strain GIMV4.0001, a
RT genetic manipulable producer of the benzoisochromanequinone antibiotic
RT granaticin.";
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP010407; AJF69039.1; -; Genomic_DNA.
DR RefSeq; WP_041132960.1; NZ_CP010407.1.
DR AlphaFoldDB; A0A0B5IKX6; -.
DR STRING; 362257.SVTN_36845; -.
DR KEGG; svt:SVTN_36845; -.
DR HOGENOM; CLU_037628_6_4_11; -.
DR Proteomes; UP000031774; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06296; PBP1_CatR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000031774};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 6..61
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT DOMAIN 7..50
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 337 AA; 36103 MW; BB150D65DD63BE71 CRC64;
MSEQRATLAV IAAEAGVSQA TVSKVINGRS DVAPSTRERI EGLLRSHNYL QPGRQNRARR
SGLVDLIIGG LDSAWAVEIL RGVEAECAQR GVGTVVSLVP PGEATPSSWS ALPVQHHSDG
VILVTASVTE AQRAQVERGG VALVVIDPID LPDNGVPSIG ATNWAGGLAA TEHLLELGHR
RIAAIGGRKE MLCSQARIDG YRAALERAGI EVDRDLIRFG DFQHEGGFRC AQELLALPEP
PTAIFAGSDQ QAMGVYEAAR QSGLSIPRDL SVVGFDDLPM CDWLSPPLTT VRQPLEEMGR
LAARALFQLL EDQPLVSPRM ELSTELKVRV STAPPRL
//
