ID A0A0B5IZE2_9VIRU Unreviewed; 368 AA.
AC A0A0B5IZE2;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
OS Pandoravirus inopinatum.
OC Viruses; Pandoravirus.
OX NCBI_TaxID=1605721 {ECO:0000313|EMBL:AJF98258.1, ECO:0000313|Proteomes:UP000202511};
RN [1] {ECO:0000313|EMBL:AJF98258.1, ECO:0000313|Proteomes:UP000202511}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KlaHel {ECO:0000313|EMBL:AJF98258.1};
RX PubMed=26374538; DOI=10.1007/s00436-015-4731-5;
RA Scheid P.;
RT "Viruses in close associations with free-living amoebae.";
RL Parasitol. Res. 114:3959-3967(2015).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550,
CC ECO:0000256|RuleBase:RU004279};
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|RuleBase:RU004279}.
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DR EMBL; KP136319; AJF98258.1; -; Genomic_DNA.
DR RefSeq; YP_009120493.1; NC_026440.1.
DR GeneID; 23463175; -.
DR KEGG; vg:23463175; -.
DR OrthoDB; 12695at10239; -.
DR Proteomes; UP000202511; Genome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.40.40.20; -; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 2.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 2.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279};
KW Reference proteome {ECO:0000313|Proteomes:UP000202511};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279}.
FT DOMAIN 11..364
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
FT REGION 61..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 368 AA; 38868 MW; 7409E8F4E6562DB6 CRC64;
MGCDPTNSHP SWMIITVLPV PPPIVRPSIT ETEGSRSRGQ DDLTHKLKAI VQANNAIAAH
QRASSSSAMS TTTAANPSTQ AAPIGSSNGS GNSANNKILA TPLADLVMAL QVEVATYHNN
DIRGQKQSTQ RSGKPTKGLV ERFKGKEGRI RGNCMGKRVN FTARAVISPD PEIDIDEVGV
PYEIVKTLTF PERVTPFTMG DLTRRVRAGP DALAGAKTVT DHNRRTLYLE ARGAGPGQTG
MGSDLASVER GTGGAIVSTM ATGAHAASDG SGVAGAWRVP AGGSVAGADR APPLQIGWTV
ERHLRAGDAV VMNRQPSLHM GSMLMHKVVP MPGRTMRFNL AVTGTYNADF DGDEMNLHVP
QSETRAPR
//
