ID A0A0B6TE31_9CORY Unreviewed; 1013 AA.
AC A0A0B6TE31;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=B840_02845 {ECO:0000313|EMBL:AJK68197.1};
OS Corynebacterium marinum DSM 44953.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1224162 {ECO:0000313|EMBL:AJK68197.1, ECO:0000313|Proteomes:UP000031928};
RN [1] {ECO:0000313|EMBL:AJK68197.1, ECO:0000313|Proteomes:UP000031928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44953 {ECO:0000313|EMBL:AJK68197.1,
RC ECO:0000313|Proteomes:UP000031928};
RA Schaffert L., Albersmeier A., Kalinowski J., Ruckert C.;
RT "Complete genome sequence of Corynebacterium marinum DSM 44953.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
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DR EMBL; CP007790; AJK68197.1; -; Genomic_DNA.
DR RefSeq; WP_042620874.1; NZ_CP007790.1.
DR AlphaFoldDB; A0A0B6TE31; -.
DR STRING; 1224162.B840_02845; -.
DR KEGG; cmq:B840_02845; -.
DR HOGENOM; CLU_004900_0_0_11; -.
DR OrthoDB; 5240387at2; -.
DR Proteomes; UP000031928; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF59; DNA HELICASE; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000031928}.
FT DOMAIN 17..305
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 273..568
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 38..45
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1013 AA; 109132 MW; 4ABACA10126D9ABC CRC64;
MTSLPPIPVV RLTARDKNLP RRTWDADLPA SGVWRVTGPA GSGVTSLLID TVLARIDAGE
DPTGILVVAA SKETGAIIRR ELTDRLSGTD FASEAPLVRS VHSLAFALLR DASEEPVRLM
TGAEQDAVIR ELLAGHAEEG RGTWPDEHRP ALTFVGFARQ LRDFLLRAAE RGLSPEDLEE
LGRTHGRPIW TAAGGFLREY EQTMSLSSAS SYTSYSASEL VAAALEKPLA SRWHTLVVDD
AQHLDPTSAE LVRRLIPGTD LVVVGGDPEQ SIFRFRGASP AFLTELPVDH EIVLTGSLRT
PEREVVVVDS FPTQNALIAD RLRRAHLLAG VPWSDMAVVV RSTGQIAPVR RALLAAGVPV
HISPTDVVLA EQRIVSNLLL GIRGLTEELT SSELQDLLLG PVGGADPVTL RRLIRGLRRF
DPATRGIDTL RGLLLPDADM PDFGGLLTER ERSILARICG VLEAGRAAMK TGSVEEILWA
VWSATGLSDH LLASALRGGA GGSQADRDLD AVMSLFDAAG DYAERRPTGS IRSFITHITE
QELPTGVRDR RTAAPQAVTL LTAHGTVGGE WGHVIVAGAQ EGDWPSLGET GSIFDQEELV
ELLDAGVDPN VPVSRTADRL KEERRLFHVA VTRATATLLV TAVNCPDADE PTEPSRFVDE
FALAHGLAPQ RFCADPAGEA GDYQRLHVRL LSVPALLAEL RRTASDPAAR ADERAQAARQ
LARLAQAGVP GADPAEWWTT TAPSTMEPLP TAPALSPSRI EGLLNCPLRE VIQRLVAEED
TPAALTRGTL AHAYLEAVGR GVDTQQAKDL TLAAWDQVQN DPEWRVATER ESLARLLDRT
SLWLTQSRSR MTLVGAELDL DVAVDEGVRI RGRMDRLEVD ESGDHWVVDL KTGGQAVSQP
AAQQHVQLTA YQLALRNGAL HDGRVTDLAP GDEGLPVGGG VLVYPGTKTK DVSTREQAAH
PPEVLDEFAS LLPGLVRELR GPTLTARIND GCERCPVRAI CPLQPEGKAT TRV
//
