ID   A0A0B7FIC4_THACB        Unreviewed;       340 AA.
AC   A0A0B7FIC4;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Enoyl reductase {ECO:0000313|EMBL:CEL55917.1};
DE            EC=1.3.1.- {ECO:0000313|EMBL:CEL55917.1};
GN   ORFNames=RSOLAG1IB_01929 {ECO:0000313|EMBL:CEL55917.1};
OS   Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14) (Lettuce bottom
OS   rot fungus) (Rhizoctonia solani).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX   NCBI_TaxID=1108050 {ECO:0000313|EMBL:CEL55917.1, ECO:0000313|Proteomes:UP000059188};
RN   [1] {ECO:0000313|EMBL:CEL55917.1, ECO:0000313|Proteomes:UP000059188}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rhizoctonia solani AG1-IB 7/3/14 {ECO:0000313|EMBL:CEL55917.1};
RA   Wibberg Daniel;
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the steroid 5-alpha reductase family.
CC       {ECO:0000256|ARBA:ARBA00007742}.
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DR   EMBL; LN679101; CEL55917.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B7FIC4; -.
DR   STRING; 1108050.A0A0B7FIC4; -.
DR   Proteomes; UP000059188; Unassembled WGS sequence.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd01801; Ubl_TECR_like; 1.
DR   Gene3D; 1.20.120.1630; -; 1.
DR   InterPro; IPR001104; 3-oxo-5_a-steroid_4-DH_C.
DR   InterPro; IPR039357; SRD5A/TECR.
DR   PANTHER; PTHR10556; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; 1.
DR   PANTHER; PTHR10556:SF28; VERY-LONG-CHAIN ENOYL-COA REDUCTASE; 1.
DR   Pfam; PF02544; Steroid_dh; 1.
DR   PROSITE; PS50244; S5A_REDUCTASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000313|EMBL:CEL55917.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000059188};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        295..314
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          234..314
FT                   /note="Steroid 5-alpha reductase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50244"
SQ   SEQUENCE   340 AA;  38284 MW;  21E5ABBADF8607F1 CRC64;
     MVSIKLQAAS SRPLAIAKNL PSTLEFPGQT LEAITIGEVK QAIAKQCPQF YAERQRITAT
     PPVKPADKNS KVVKPRALTD KTTLQDAGLD ASNSTLYLKD LGTQVSYRTV FIVEYIGPLL
     IHPVVYHLPK LIYRKDVQHS QLQTVAYALV MLHFLKRELE TIFVHRFSHA TMPVGNLFRN
     SAHYHLLSGL LLSLALYGPW YSQGSLSAKH ASAPSILLGW GWPSNNTASL AKWIAIWAFA
     ELSNLHAHLT LRNLRPANNP TARGIPRGYL FEYVSCPNYT FEILAWIAFT LMTKSWASLI
     FIIAGTTPMV IWAIKKHKAY RREFGSQYPR NRKIIVPFLF
//