ID A0A0B7HZW8_9FLAO Unreviewed; 489 AA.
AC A0A0B7HZW8;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=K(+)/H(+) antiporter NhaP2 {ECO:0000313|EMBL:CEN49479.1};
GN Name=nhaP {ECO:0000313|EMBL:CEN49479.1};
GN ORFNames=CCAND38_80124 {ECO:0000313|EMBL:CEN49479.1}, CCAND93_400028
GN {ECO:0000313|EMBL:CEN53359.1};
OS Capnocytophaga canis.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Capnocytophaga.
OX NCBI_TaxID=1848903 {ECO:0000313|EMBL:CEN49479.1, ECO:0000313|Proteomes:UP000045051};
RN [1] {ECO:0000313|Proteomes:UP000038200, ECO:0000313|Proteomes:UP000045051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CcD38 {ECO:0000313|EMBL:CEN49479.1,
RC ECO:0000313|Proteomes:UP000045051}, and CcD93
RC {ECO:0000313|EMBL:CEN53359.1, ECO:0000313|Proteomes:UP000038200};
RA MANFREDI Pablo;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CDOI01000195; CEN49479.1; -; Genomic_DNA.
DR EMBL; CDOL01000229; CEN53359.1; -; Genomic_DNA.
DR RefSeq; WP_042008163.1; NZ_WLVG01000002.1.
DR AlphaFoldDB; A0A0B7HZW8; -.
DR STRING; 1848903.CCAND38_80124; -.
DR OrthoDB; 9810759at2; -.
DR Proteomes; UP000038200; Unassembled WGS sequence.
DR Proteomes; UP000045051; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR PANTHER; PTHR32507:SF7; K(+)_H(+) ANTIPORTER NHAP2; 1.
DR PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02080; TrkA_C; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR PROSITE; PS51202; RCK_C; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000045051};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 405..487
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 489 AA; 53477 MW; 02B402967A7F1AB9 CRC64;
MNLTSENILL VGSLLLLVSI VAGRTSYKFG VPTLILFLGV GMLAGSDGIL KIEFNNPGLA
QFIGILSLNF ILFSGGLETR WKSVQPILGQ GIMLSTVGVL LTAVFLGVFV WYVTDFTIFE
SLLLGSIVSS TDAAAVFSIL RSKNLELKEN LRPTLEFESG SNDPMAYVLT TTFLGLVQIP
DQDLLGVIFI FLKQIILGGI LGFIFGRLSK IIFNRISLGF EGLYPVLAIA LMYITFSGTE
ALGGNGFLAI YVAAVYLGNH SFIHKGSVIK MFDGLAWLMQ IVMFLTLGLL VNPSETIPLM
GIGLLISVFL ILVARPLSVF LGTLPFKMSF ARRSYISWVG LRGAVPIVFA TYPMLAGLEK
ANIIFNIVFF ISVTSVLIQG TTLSMVAKWL NLASEQPAEN EENPADAIKR EHPRAVMQEI
FIPEDCYVVD KKIVDVDFPS NAIIAMIKRK DKYITPNGST QIEGNDTLIV ISDNTQVMDE
VRNALELES
//
