ID   A0A0B7MLY1_9FIRM        Unreviewed;       490 AA.
AC   A0A0B7MLY1;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Putative aldehyde dehydrogenase AldA {ECO:0000313|EMBL:CEO88971.1};
DE            EC=1.2.1.3 {ECO:0000313|EMBL:CEO88971.1};
GN   Name=aldA {ECO:0000313|EMBL:CEO88971.1};
GN   ORFNames=SSCH_320003 {ECO:0000313|EMBL:CEO88971.1};
OS   Syntrophaceticus schinkii.
OC   Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacterales Family III. Incertae Sedis; Syntrophaceticus.
OX   NCBI_TaxID=499207 {ECO:0000313|EMBL:CEO88971.1, ECO:0000313|Proteomes:UP000046155};
RN   [1] {ECO:0000313|Proteomes:UP000046155}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sp3 {ECO:0000313|Proteomes:UP000046155};
RA   Manzoor Shahid, Zubair Saima;
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CDRZ01000228; CEO88971.1; -; Genomic_DNA.
DR   RefSeq; WP_044665026.1; NZ_CDRZ01000228.1.
DR   AlphaFoldDB; A0A0B7MLY1; -.
DR   OrthoDB; 9762913at2; -.
DR   Proteomes; UP000046155; Unassembled WGS sequence.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345};
KW   Reference proteome {ECO:0000313|Proteomes:UP000046155}.
FT   DOMAIN          20..478
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        251
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   490 AA;  53372 MW;  63C0194D482486AC CRC64;
     MTIKLQETYG MYINGEFVGA ASGKTFDSIN PATGEKLAAI AYGDVTDVDK AVAAAWEAFP
     AWGKTSTRER SEILWKISNV IEANIEYLAE IETLDNGKPI EESRWDMWDA VDEFRYFASC
     IRSDEGLFVE HDDASFSILR REPLGVVGQI VPWNYPICMG CWKLAPALAA GNCIVFKPAS
     NTSISILELA KLIGDILPSG VLNIVTGSGS VCGTALSKHK GIRKIAFTGS TEVGRQIGAN
     AGQNIIPSTL ELGGKSAHII FADCQWERAM IAAQSNILFN SGQICCAGSR LFIQEEIYDK
     FLTELAARFN AVKVGNGLDP ETQMGPVIDE SQMKKILEYI DIGVKEGARL VAGGKRLTGN
     GYDKGFFIAP TILADVDNKM RVAQEEIFGP VLVVLKFKDE DDVIAMANDS CYGLAGGVWT
     QDINKALRVA KALQGGTIWV NEYGISPAGS AFGGYKDSGY GREVHKQILD HYTQCKNILI
     NTTEEPYDFY
//