ID A0A0B7MRX5_9FIRM Unreviewed; 453 AA.
AC A0A0B7MRX5;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Polynucleotide adenylyltransferase/metal dependent phosphohydrolase {ECO:0000313|EMBL:CEO90427.1};
GN ORFNames=SSCH_870027 {ECO:0000313|EMBL:CEO90427.1};
OS Syntrophaceticus schinkii.
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacterales Family III. Incertae Sedis; Syntrophaceticus.
OX NCBI_TaxID=499207 {ECO:0000313|EMBL:CEO90427.1, ECO:0000313|Proteomes:UP000046155};
RN [1] {ECO:0000313|Proteomes:UP000046155}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sp3 {ECO:0000313|Proteomes:UP000046155};
RA Manzoor Shahid, Zubair Saima;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the tRNA nucleotidyltransferase/poly(A)
CC polymerase family. {ECO:0000256|RuleBase:RU003953}.
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DR EMBL; CDRZ01000288; CEO90427.1; -; Genomic_DNA.
DR RefSeq; WP_044666186.1; NZ_CDRZ01000288.1.
DR AlphaFoldDB; A0A0B7MRX5; -.
DR OrthoDB; 9805698at2; -.
DR Proteomes; UP000046155; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0031123; P:RNA 3'-end processing; IEA:UniProt.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR CDD; cd05398; NT_ClassII-CCAase; 1.
DR Gene3D; 1.10.246.80; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR InterPro; IPR032810; CCA-adding_enz_C.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002646; PolA_pol_head_dom.
DR InterPro; IPR032828; PolyA_RNA-bd.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR46173; CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR46173:SF1; CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR Pfam; PF01743; PolyA_pol; 1.
DR Pfam; PF12627; PolyA_pol_RNAbd; 1.
DR Pfam; PF13735; tRNA_NucTran2_2; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81891; Poly A polymerase C-terminal region-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:CEO90427.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:CEO90427.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000046155};
KW RNA-binding {ECO:0000256|RuleBase:RU003953};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003953}.
FT DOMAIN 24..148
FT /note="Poly A polymerase head"
FT /evidence="ECO:0000259|Pfam:PF01743"
FT DOMAIN 175..235
FT /note="tRNA nucleotidyltransferase/poly(A) polymerase RNA
FT and SrmB- binding"
FT /evidence="ECO:0000259|Pfam:PF12627"
FT DOMAIN 302..444
FT /note="CCA-adding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13735"
SQ SEQUENCE 453 AA; 51762 MW; F68DDBBE21C5ABA2 CRC64;
MNLLIPKEVR DACILLARHR KQSFVVGGGM RDLILGMPPQ DWDLATDARP REVERIFKAC
GYRVVPTGVK YGTVTVKKNG LPLEITTFRV EACYRDHRRP SRVNFVSEIE DDLGRRDFTI
NALAYDPLRS FFCDPYQGIP DLIKEQIRAV RDPEERFSED PLRMLRAVRI AAELGFSIED
KTMHAMIRNA ELLGKISAER IRDELNRLLM APHFHQGLEN LLEACLLFVI IPELKEGWLF
NQYHPSHQYP VLPHTLEAMR YTPANLEVRL AILLHDVAKP RCYSRGEDGR GHFYGHNVVG
AEMAEEILRR LHYSNQVINN VVMLVREHML ELKMGPAGMR RLIARIGRGM VPALLSVRLA
DILAHSRSQV VRSLEEYEKF SKNLEQVMAT GDAFVMRELA VNGSDIIQET GVPPGPLVGK
ILQHLWEEVL DDPKKNNRDY LLALAKRMIN TPG
//
