ID A0A0B7N5S8_9FUNG Unreviewed; 2268 AA.
AC A0A0B7N5S8;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=PARPA_04618.1 scaffold 14707 {ECO:0000313|EMBL:CEP10830.1};
OS Parasitella parasitica.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Parasitella.
OX NCBI_TaxID=35722 {ECO:0000313|EMBL:CEP10830.1, ECO:0000313|Proteomes:UP000054107};
RN [1] {ECO:0000313|EMBL:CEP10830.1, ECO:0000313|Proteomes:UP000054107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 412.66 {ECO:0000313|EMBL:CEP10830.1,
RC ECO:0000313|Proteomes:UP000054107};
RA Ellenberger Sabrina;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN725407; CEP10830.1; -; Genomic_DNA.
DR STRING; 35722.A0A0B7N5S8; -.
DR OrthoDB; 1222064at2759; -.
DR Proteomes; UP000054107; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43719:SF28; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK2; 1.
DR PANTHER; PTHR43719; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000054107};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 1..325
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1714..1941
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 2122..2246
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 765..789
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1681..1708
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 2174
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 2268 AA; 254969 MW; E6CB0F785F6D16CB CRC64;
MKNLINSADL ETAFQVTGYH FDKPVLLEGV DNVAIAHGIR NRDRLPVVAK LSHQPLRLER
EYHIVQRLYR QPSAKDLLCK PLDRITLSDD SLIAFIYEDF RDNLLEKYQP GSTSEFLQQS
LIALNDKHPS DFMSMHQFLE FAIQCCNCLE MIHKHQIVHG EIKLNAFLWP KGHSVKIWNF
GSGSRSLEQS LTSEGWRKTV QRNGANNFLQ MLMYMSPEQT GRTTFQPDHR TDLYSLGITF
FVALTQSMPF AHSSPMEIVH NVLNKKLPSV HEVRPETPVV VSMIIEKLTN KSPDERYTSA
HGLREDLKEC QKQLQHGTGM LKPFLLGKFD IASIFTLPNN GCFGRAKELS LISAIIRRTA
YMCGFNIRRR RSNSDMAATA AAALFTPLKL TTEEQSPTYK RVHNRNEALD GKSSSKVHHN
RKRPTEIIAI YGNTGVGKST LVRNVQQFAR EYGYIAIAKF DTRQPTPYGC ILRCLSIFLK
NILTEPASEI ERFGRMLKEQ LGAETMAQLP TLLVDNVPEL ASFLDQPLLQ SAPVANSNQS
SGCECDMEGG EIKLRFHSAF IEIFQAMVNF KFVTLFLEDL HQADEASIEL LDSLISAKLN
FLVILTYRKN EVSSLITKLL RNEDSIVSYI KIENLDQTAL MELVRTTMHR LEEIDLALLT
PLVEFIYKRT HGNPFYACQL LMTLEKKNII YFTWEKTRWE YNLQEIDKAL LLYMKEDNNG
DMDIAFLVQR LEELPRDGRR FLKWASFVGN SFSYETVRNL MMENQDMDDT NNGQDDSDSS
DQDQDSSSVS KAIAGRRKFD AINGLQSALQ QGFIQAFSND EFKFTHDRYS QAAMMLASPA
TQDAFHLKIA SHFMTKDSVD KFWVADHVKA ALHLIKNKPS KSSYRKVLLQ AGDKAFDSGA
HKLAFSYYSA AQELLTTSED PWKDGRDAAY AETLHLYTRL AEISWFMDYD LTRGYLTAIL
DHAQSAIDRA AAYRVQHRYR WSRAGSQESA PILLECLREL GVDDIQMDTM SEEDQEKLYT
ATRNEVLKVG MSNLLNLPVC ESRLIRTRFS IMEELCLWAY WTNDMRAMLA VGSRFVLKTL
RNGTTPTTGV GFVFFGIAVM QLFKAYEFGE QIGAIGVALC NSYGGNSESG RARYLYAAFL
SSWKHPYRKS ISMARLAMKQ GLLGGDRIYA TFAHSYVVIG SLLTGENMAD VLRDAKTCVE
EANSLGETVG TSILATAIVR VILAVQGKTQ LSPESIFNGK DFSEARFVQQ AMQEHPDSDI
QLYYYYAMKS IILGFFEFDA ASIQLSSQHT HMSDALPSAR HTHLMFFFRC VSFIRLMKSG
EISLVNMSEM EKSRARLANW AWHSHPTNLG MFVTCIDAEL AGLHNEPLKA QKLYDQAIRQ
AREGNWPLET AVIHELAGAF YHQNDLTTVA CALLKDALRS YRHMGLFGKA NHLELKYRSL
LLQESSSSSS EQATKDASVQ TETFQTIVKR ESISDLTVPE PYSADTFNSQ ANSVNNTSPE
ETLLTLDVVD LASILKSSQV ISSEMNFELL MKQMLGIILE NSGAESGVII VKENTSFLIV
GCGSQTHGCE IFTKPKPLSE EADSIITRVS HYAIHAQESL FIVDVQQDSR FSDCTTQAKS
CICTPIIHKT AIVGCIYIEG AVGSLTCRHE VVLRLLSQQI GISVTNALLF KSIQKVTYAN
VKMIENQKAA LEEARKSKEA ALHAMRLKAD FLANMSHELR TPFSGFYGMI SLLSETSLDA
EQQDIVHTAK ESCEMLLKII DDLLNFSKLE AGKVALDLGP LVVEEVIADT IEILSSLSAR
KGLELAYYVD PEVPDTIITD SSRLRQILTN LLGNAIKFTH QGGVVIKCHV VQDDVEFADS
DEFVRLKFEV IDTGIGIRPE QQRQLFEPFS QVDGSTTRMY GGTGLGLSIC LQLVRLMLGQ
VGVESEPEEG SNFWFTIVAN KVPKRIEDAN SVSKIAALQV SLRGQAILLA SYSDLNAKMV
RSLLADFTIQ RTADMHQAVP RALQEHHPIL ILDIPAKPSN FIAHQIQSVD DDPECELHII
LLYTPSTEGH KLAAEATNSA SDRRGRLVKM AKPVRRAKLL SVLEQVLDQQ RVAPMPQLPT
PLGNRMQDYF EKEELSWYAQ KPVLIAEDNM VAQKLLRKQL EKMGFLVESA NNGEEAVSLW
RERPPNYFCL GFFDHHMPKV SKCDGVEATK RIRAFESGTN SRLPIVALTA DIQSSAKEIC
FNAGMDGYLT KPLIPKELAT TLRSLNLVVQ KHYDTPSSST PSSPLYSV
//
