ID A0A0B7N858_9FUNG Unreviewed; 448 AA.
AC A0A0B7N858;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 22-FEB-2023, entry version 31.
DE RecName: Full=Hsp90 chaperone protein kinase-targeting subunit {ECO:0000256|ARBA:ARBA00031396};
GN Name=PARPA_05483.1 scaffold 18426 {ECO:0000313|EMBL:CEP11608.1};
OS Parasitella parasitica.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Parasitella.
OX NCBI_TaxID=35722 {ECO:0000313|EMBL:CEP11608.1, ECO:0000313|Proteomes:UP000054107};
RN [1] {ECO:0000313|EMBL:CEP11608.1, ECO:0000313|Proteomes:UP000054107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 412.66 {ECO:0000313|EMBL:CEP11608.1,
RC ECO:0000313|Proteomes:UP000054107};
RA Ellenberger Sabrina;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the CDC37 family.
CC {ECO:0000256|ARBA:ARBA00006222}.
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DR EMBL; LN726622; CEP11608.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B7N858; -.
DR STRING; 35722.A0A0B7N858; -.
DR OrthoDB; 1329460at2759; -.
DR Proteomes; UP000054107; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0019901; F:protein kinase binding; IEA:InterPro.
DR Gene3D; 1.20.58.610; Cdc37, Hsp90 binding domain; 1.
DR InterPro; IPR004918; Cdc37.
DR InterPro; IPR013873; Cdc37_C.
DR InterPro; IPR013874; Cdc37_Hsp90-bd.
DR InterPro; IPR038189; Cdc37_Hsp90-bd_sf.
DR InterPro; IPR013855; Cdc37_N_dom.
DR PANTHER; PTHR12800; CDC37-RELATED; 1.
DR PANTHER; PTHR12800:SF4; HSP90 CO-CHAPERONE CDC37; 1.
DR Pfam; PF08564; CDC37_C; 1.
DR Pfam; PF08565; CDC37_M; 1.
DR Pfam; PF03234; CDC37_N; 1.
DR SMART; SM01069; CDC37_C; 1.
DR SMART; SM01070; CDC37_M; 1.
DR SMART; SM01071; CDC37_N; 1.
DR SUPFAM; SSF101391; Hsp90 co-chaperone CDC37; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000054107}.
FT DOMAIN 2..182
FT /note="Cdc37 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01071"
FT DOMAIN 185..359
FT /note="Cdc37 Hsp90 binding"
FT /evidence="ECO:0000259|SMART:SM01070"
FT DOMAIN 374..448
FT /note="Cdc37 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01069"
FT REGION 174..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 448 AA; 50192 MW; 86332FF310A4A966 CRC64;
MPLDYSKWDN LELSDDSDIE VHPNVDKRSM IKWKQEAIHR ERAERKAKID SLTQFVPQQE
AVLKKVQELT SMLKDNDDDL AGIKKVVEML DKQQTEADPK MKVPSAAGKE IDVAQVFAAM
KTQIATGLAS NSPAEVKKTL LDRFSQTEAT VQKTVTEASR ELAKLNKEAS KKLTSDNMFT
SEKSNKTILN KPKPTPKKSE KKKVIETLNP NAAMKDLSLD TSNDADNEDE DDGDQDIDMS
PKAAEFSKIK GFEASYKYLE RNSDIINEKT SDSILGQAFT AQLKGDEDYA KNCVIQSLML
VYCGQLGKDG VSLFFSRMGS PNTQGRKMFF DDVEKKYSHI QSRCAEIAAE EVTEENGVET
IQLQSMGDGT QLTIRVPEPE HEEAYKVFTA MPSNFRDALK TGKLDEINKV LEKIAVPEAE
ELVQLCSEYG FLDVESEVID ETQLEKAQ
//
