ID A0A0B7NA88_9FUNG Unreviewed; 773 AA.
AC A0A0B7NA88;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Ras-GEF domain-containing protein {ECO:0000259|PROSITE:PS50009};
GN Name=PARPA_05790.1 scaffold 19890 {ECO:0000313|EMBL:CEP11889.1};
OS Parasitella parasitica.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Parasitella.
OX NCBI_TaxID=35722 {ECO:0000313|EMBL:CEP11889.1, ECO:0000313|Proteomes:UP000054107};
RN [1] {ECO:0000313|EMBL:CEP11889.1, ECO:0000313|Proteomes:UP000054107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 412.66 {ECO:0000313|EMBL:CEP11889.1,
RC ECO:0000313|Proteomes:UP000054107};
RA Ellenberger Sabrina;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN727106; CEP11889.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B7NA88; -.
DR STRING; 35722.A0A0B7NA88; -.
DR OrthoDB; 1359851at2759; -.
DR Proteomes; UP000054107; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR Pfam; PF00617; RasGEF; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Guanine-nucleotide releasing factor {ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000054107}.
FT DOMAIN 71..304
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 394..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..743
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 38..65
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 408..422
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 493..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 621..641
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 647..662
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..743
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 773 AA; 86546 MW; 751CF0ED531FF582 CRC64;
MRLPLIPLSP YIHTSCEYAK VLAQTTKSLS EEESASIRTL LEKNLHKERE KLDRLTENMQ
SIQSSCLLDF NIYDIAKEIA YINCSLFRMV TLDKHWLCIF DKQSNIVPLL DFHRYLSHSF
AHQIIYGDPK RKSVIQLIHL AYILLHVYRD FSGCTAILRS LYMPEVRRLQ GMWEPCPPKL
IQVYEELVAM LSPDNNYEAY HHQLWVHTNR FLNITPSKSQ MIAIPFMQAH LATIQQLVQT
HASVQAAADV VLSSAGQPLL DSTVHLLEFC QQFSEIDPPE LEKYSSPPAS ATVSRRLSFQ
SSVSSSNRRS SILGSSKAIK LSTSPCLNLD HLRSNAKVYH WIVSRAYLSR SQLHSESLHV
EPLAVGENEL EVEEEDDLYW VFFNKDFAAK DTATEALKKD PPTKPSRSPS KAILTGNQDP
VQETVDGLDV VDNSDHTTDQ TAASLISAVN TNDAQNSEQE AAAAAEEPTS SISKGEPDDS
AIAADNAALE ANDDKPNTLN IQTLETNEEQ EQQPNEENQE QPEEETNKQT SENEPAKVQD
VQGSVALPPS PLLPSASSNM LQVDSQGEDS KKTSSIVGND DDDDEDDLVI LTEEDKEKWT
GYPFKRTLSP TFSETGEEEK WTGYPIPKEE EDDEEVWKGY PMPSSEKEYK VQQQQQGFPS
NGKSDDDKGE ESPVVISLPS TPSEEEEWKG YKNEQQQQQQ QQQQQTIVVT TDDTASDIRD
PHISSWNDNN GTSRNSQTLA AGNTTAVRMQ YSVSTTVTNS RTLPSPFAPS SST
//
