ID   A0A0B7NLG3_9FUNG        Unreviewed;      1242 AA.
AC   A0A0B7NLG3;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN   Name=PARPA_10629.1 scaffold 41546 {ECO:0000313|EMBL:CEP16365.1};
OS   Parasitella parasitica.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Parasitella.
OX   NCBI_TaxID=35722 {ECO:0000313|EMBL:CEP16365.1, ECO:0000313|Proteomes:UP000054107};
RN   [1] {ECO:0000313|EMBL:CEP16365.1, ECO:0000313|Proteomes:UP000054107}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 412.66 {ECO:0000313|EMBL:CEP16365.1,
RC   ECO:0000313|Proteomes:UP000054107};
RA   Ellenberger Sabrina;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC         ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC       ECO:0000256|RuleBase:RU363098}.
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DR   EMBL; LN733128; CEP16365.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B7NLG3; -.
DR   STRING; 35722.A0A0B7NLG3; -.
DR   OrthoDB; 2735303at2759; -.
DR   Proteomes; UP000054107; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   PANTHER; PTHR23079:SF14; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   Pfam; PF05183; RdRP; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054107};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
FT   REGION          149..184
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          674..694
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1056..1090
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1242 AA;  140399 MW;  3688D65F7F6B15D4 CRC64;
     MPTLEPVIIR CAKQIYHNLK LTHRIRLLAN AATNTSLPPE VVKMQQLVAI ADGKTLEKIV
     RSFLQDTRPN KSLNEFVALL DEENQMLIGM NDAFNDEFEE EFQDEFDDDC VDIFAQIMET
     TPEPKKRARL PSLDVNTVSH KRLKVATVNT SSTTGNSTAT TTATTRSSIS FNQPTPSKAT
     PSPLTVRKAT PLTLVIDQES CFFNDTSQSE THNTICNPQC ASKLFQGVPW VILYEISRFV
     QAFNVDWSLI PFEAFQTFIN TGNNEPAQLY DTMIKWNQET RLGIKVNGSA YTVMDRCPEN
     VWVYFKQTQR PTTVPSTPVT PLPSALDPNF AVQSKDQNAR IKNRMIHFSG LITWKKSHLP
     PTITLRAPKV EASNRFFRKF GQDRFLELKL SKTTHVAILK QHKKFFLKPF LLMHRVFRFL
     FVKDDTIIMF ATEGVDLTPI SIQQVIDWHM PITENWDMSM SKYASRMSLG YSSSIPTFEF
     KPEEIIYIDD VYGSTASDSN ETNCMTDGCG IISCSAMKKI MGCQATEELP CAIQGRIAGA
     KGIWIIAPDL DFSTGDYIKI RKSQDKFKTG LPQSDFSLDP HHYTFDLVKN SILVYPSYLN
     TQFIQCLSHG GVPHSVFIVI LKEYIHQLAA IVTENQSIKL LRDWVAKSGK IMLGRWEGEA
     NTEKGLWRDL VSGGSSGGGG GDDENDSGFF TLDSPDDIHS NDDETLDSSG GEEKGLNKLA
     IDNKENHFAR LNKYSGFPAS LHESIVRLLD AGFDLSNAYV ATRVTMVFRQ IMQAITTKYK
     IEVPQSCTVT CVPDPTGTLE PGEIFLQLSS RRVDEKTGIR AGQILGDVLV TRNPCALQSD
     VQKVFCCWDE RLVKPFNSKP VPPPCKRAEE AFVKDKNTVG REVSSNKNTE EAIQGNFISV
     AIPDGTLGVY ENWRTVLAEC TSLDHPDVVY LGHMCSKLVD AAKQGLTLKA TVKKQDRANF
     SEIPHPPWFM DKKNKQRAST FRSYKEVNNV YTLEGAPCTT TMDFLYDTLL SETAAFTKYS
     RSMFCDDDVA LKDPDLIAPW LKAKELATQL NDELLAADLR LIADAVEKNK REYNEQCTKL
     DSQKQRYLEN ISNPTKYVDE KYMEEFQSQF NSHFQLEEFY AKDFFESPPT QSLKSNVMTF
     DVQANGGRML QNIKASYAYI TSINTNKYAK YCYLVAYDHL RRIKADATAK QTKENGIAET
     LSSSAYKCMT IDRKWIKKMK ETNYTENNER VRLSTEYIPN KS
//