ID A0A0B8N926_9NOCA Unreviewed; 605 AA.
AC A0A0B8N926;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=pyruvate kinase {ECO:0000256|ARBA:ARBA00012142};
DE EC=2.7.1.40 {ECO:0000256|ARBA:ARBA00012142};
GN ORFNames=NS07_v2contig00006-0058 {ECO:0000313|EMBL:GAM44668.1};
OS Nocardia seriolae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=37332 {ECO:0000313|EMBL:GAM44668.1, ECO:0000313|Proteomes:UP000019401};
RN [1] {ECO:0000313|EMBL:GAM44668.1, ECO:0000313|Proteomes:UP000019401}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N-2927 {ECO:0000313|EMBL:GAM44668.1,
RC ECO:0000313|Proteomes:UP000019401};
RA Imajoh M., Fukumoto Y., Yamane J., Sukeda M., Shimizu M., Ohnishi K.,
RA Oshima S.;
RT "Draft Genome Sequence of Nocardia seriolae Strain N-2927 (NBRC 110360),
RT Isolated as the Causal Agent of Nocardiosis of Yellowtail (Seriola
RT quinqueradiata) in Kochi Prefecture, Japan.";
RL Genome Announc. 3:e00082-15(2015).
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-
CC glyceraldehyde 3-phosphate: step 5/5. {ECO:0000256|ARBA:ARBA00004997}.
CC -!- SIMILARITY: Belongs to the pyruvate kinase family.
CC {ECO:0000256|ARBA:ARBA00008663}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAM44668.1}.
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DR EMBL; BAWD02000006; GAM44668.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B8N926; -.
DR STRING; 37332.NS506_05159; -.
DR UniPathway; UPA00109; UER00188.
DR Proteomes; UP000019401; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0030955; F:potassium ion binding; IEA:InterPro.
DR GO; GO:0004743; F:pyruvate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 2.
DR Gene3D; 2.40.33.10; PK beta-barrel domain-like; 2.
DR InterPro; IPR001697; Pyr_Knase.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR InterPro; IPR011037; Pyrv_Knase-like_insert_dom_sf.
DR InterPro; IPR015793; Pyrv_Knase_brl.
DR InterPro; IPR015806; Pyrv_Knase_insert_dom_sf.
DR PANTHER; PTHR11817:SF76; PLASTIDIAL PYRUVATE KINASE 4, CHLOROPLASTIC; 1.
DR PANTHER; PTHR11817; PYRUVATE KINASE; 1.
DR Pfam; PF00224; PK; 1.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR SUPFAM; SSF50800; PK beta-barrel domain-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:GAM44668.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Pyruvate {ECO:0000256|ARBA:ARBA00023317, ECO:0000313|EMBL:GAM44668.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019401};
KW Transferase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:GAM44668.1}.
FT DOMAIN 346..559
FT /note="Pyruvate kinase barrel"
FT /evidence="ECO:0000259|Pfam:PF00224"
FT REGION 562..583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..577
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 605 AA; 65688 MW; B891AB0BDC5705FE CRC64;
MRIGDLDRII TEIDTLRDAL ADAERQWAVR IAGVDPRHRA GALNLVHYWA IRQFDLRGLQ
RRLAAFGLSS LGRSQGHVAS TLNAIGTAAR ALAHSDDPDR LPPNGYTAGA NVLRRRTFEL
LGPAPARRST RIMVTLPGTA AADPQLIADL VDRGMDVARI NCAHDDPAAW AAMITELRRE
GPRSCRVAMD LAGPKLRTGP IAQGPPVVKL RPVRDVLGRV TETAWCWLTP IDRPGPPPRA
DVPVLPVDAA WLSKLAPTST FRLQDARDAK RLFTVVHADA GGALACTGRT AYILAGTKLV
ADTGVITEVG PLPPVEQHLV LSPGDTLLLT RDCVPAEVPP RGLPRIGCTL PEVFGNVRRR
QPILFDDGRI TGRILDCDAD TITVTITEAT APGSKLRAGK GINLPETTLP VPALTETDRA
NLPFVIEHAD LVEMSFVRTR QDVSDLLAAL DELGGDGLGV IVKIETAQGF RNLPAILLEV
MRRPRAGVMI ARGDLAVECG YERLAELQEE ILWLCEAAHL PVIWATQVLD QLARSGRPSR
AEITDAAMGV RAECVMLNKG AVHRRRGRHP RRHPAAHERP RRQADHLHAL SAVLVSRRNA
AGDRC
//
