ID A0A0B8NE57_9NOCA Unreviewed; 650 AA.
AC A0A0B8NE57;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Nitrite reductase (NADH) {ECO:0000313|EMBL:APB00836.1};
DE EC=1.7.1.15 {ECO:0000313|EMBL:APB00836.1};
DE SubName: Full=Pyruvate oxidase {ECO:0000313|EMBL:GAM50055.1};
GN ORFNames=NS07_v2contig00135-0010 {ECO:0000313|EMBL:GAM50055.1},
GN NS506_06805 {ECO:0000313|EMBL:APB00836.1};
OS Nocardia seriolae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=37332 {ECO:0000313|EMBL:GAM50055.1, ECO:0000313|Proteomes:UP000019401};
RN [1] {ECO:0000313|EMBL:GAM50055.1, ECO:0000313|Proteomes:UP000019401}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N-2927 {ECO:0000313|EMBL:GAM50055.1,
RC ECO:0000313|Proteomes:UP000019401};
RA Imajoh M., Fukumoto Y., Yamane J., Sukeda M., Shimizu M., Ohnishi K.,
RA Oshima S.;
RT "Draft Genome Sequence of Nocardia seriolae Strain N-2927 (NBRC 110360),
RT Isolated as the Causal Agent of Nocardiosis of Yellowtail (Seriola
RT quinqueradiata) in Kochi Prefecture, Japan.";
RL Genome Announc. 3:e00082-15(2015).
RN [2] {ECO:0000313|EMBL:APB00836.1, ECO:0000313|Proteomes:UP000180166}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EM150506 {ECO:0000313|EMBL:APB00836.1,
RC ECO:0000313|Proteomes:UP000180166};
RA Han H.-J.;
RT "Genome sequence of Nocardia seriolae strain EM150506, isolated from
RT Anguila japonica.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|ARBA:ARBA00001962};
CC -!- SIMILARITY: Belongs to the TPP enzyme family.
CC {ECO:0000256|ARBA:ARBA00007812, ECO:0000256|RuleBase:RU362132}.
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DR EMBL; CP017839; APB00836.1; -; Genomic_DNA.
DR EMBL; BAWD02000135; GAM50055.1; -; Genomic_DNA.
DR RefSeq; WP_033090557.1; NZ_WMKH01000291.1.
DR STRING; 37332.NS506_06805; -.
DR GeneID; 61150573; -.
DR KEGG; nsr:NS506_06805; -.
DR PATRIC; fig|37332.12.peg.6992; -.
DR OrthoDB; 4959782at2; -.
DR Proteomes; UP000019401; Unassembled WGS sequence.
DR Proteomes; UP000180166; Chromosome.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProt.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:UniProt.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR Gene3D; 3.40.50.970; -; 2.
DR Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR047211; POXB-like.
DR InterPro; IPR017941; Rieske_2Fe-2S.
DR InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR012000; Thiamin_PyroP_enz_cen_dom.
DR InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR InterPro; IPR000399; TPP-bd_CS.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR42981; PYRUVATE DEHYDROGENASE [UBIQUINONE]; 1.
DR PANTHER; PTHR42981:SF2; PYRUVATE DEHYDROGENASE [UBIQUINONE]; 1.
DR Pfam; PF00355; Rieske; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR Pfam; PF00205; TPP_enzyme_M; 1.
DR Pfam; PF02776; TPP_enzyme_N; 1.
DR SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
DR SUPFAM; SSF50022; ISP domain; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR PROSITE; PS51296; RIESKE; 1.
DR PROSITE; PS00187; TPP_ENZYMES; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:APB00836.1};
KW Pyruvate {ECO:0000313|EMBL:GAM50055.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019401};
KW Thiamine pyrophosphate {ECO:0000256|RuleBase:RU362132}.
FT DOMAIN 9..104
FT /note="Rieske"
FT /evidence="ECO:0000259|PROSITE:PS51296"
SQ SEQUENCE 650 AA; 68536 MW; 3CF7122C12B3DFC2 CRC64;
MESDRSAQWY RVAAEDQPGE GRVRTVSVGG HSVALSRCGD RFGALANHCP HQGGPLGEGS
IENGWLRCPW HGYDFDPISG KPPAGFDDGV ATYEVRQDDS GLYVKVPEPV APPRSMADAV
VETLVNYGVT HVFGMVGHSN LGFADAMRRA EERGELTYIG IRHEGAAAFA AAAYGKLTGR
PAACFAIAGP GSTNLLTGLY DAKLDGAPVV AISGQVRSKV RGRGAFQDLD LNTVFRDVAA
WTTTLAADSD PAELAALAVK RAIDLRGVTH LVLPDEVQPQ PSDRLAGVPA DRLLPRRTAP
DAATLARAAS LIFTARRPVL IAGHGARGAT AELRTLAELL NCPILTTFKA KGLVPEGPPL
GAGVLGRSGT PVASWLMNES DLLIVVGASF SDHTGIATYK PIVSIDDTRA GVERWNAATV
GILGDAALTL ERVAKLLRAA PERLAAVDQR PDIAARWAIW RTEKERRAND DRGQGVPAAA
VFAALSAHLP ADAVVTVDVG NHAYSLGRYL ESSGQPVLMS GYLGSIGFGY PAALGAWAAA
PDRPVVAVTG DGGFAQYAAE ITTAVKYSIP IKHILLDNGS LGKISKEQRA ADYPVWHTAL
HNPDWAEYAE LCGAKGIRVT QRDQLDAAMT ELFAADGPAL LCVAQDAELV
//
