ID   A0A0B8NJ42_9VIBR        Unreviewed;       334 AA.
AC   A0A0B8NJ42;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=dTDP-glucose 4,6-dehydratase {ECO:0000313|EMBL:GAM54710.1};
DE            EC=4.2.1.46 {ECO:0000313|EMBL:GAM54710.1};
GN   ORFNames=JCM19231_3798 {ECO:0000313|EMBL:GAM54710.1};
OS   Vibrio ishigakensis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=1481914 {ECO:0000313|EMBL:GAM54710.1, ECO:0000313|Proteomes:UP000031671};
RN   [1] {ECO:0000313|EMBL:GAM54710.1, ECO:0000313|Proteomes:UP000031671}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 19231 {ECO:0000313|Proteomes:UP000031671};
RA   Sawabe T., Meirelles P., Feng G., Sayaka M., Hattori M., Ohkuma M.;
RT   "Vibrio sp. C1 JCM 19231 whole genome shotgun sequence.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:GAM54710.1, ECO:0000313|Proteomes:UP000031671}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 19231 {ECO:0000313|Proteomes:UP000031671};
RG   NBRP consortium;
RA   Sawabe T., Meirelles P., Feng G., Sayaka M., Hattori M., Ohkuma M.;
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAM54710.1}.
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DR   EMBL; BBRZ01000006; GAM54710.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B8NJ42; -.
DR   Proteomes; UP000031671; Unassembled WGS sequence.
DR   GO; GO:0008460; F:dTDP-glucose 4,6-dehydratase activity; IEA:UniProtKB-EC.
DR   CDD; cd05253; UDP_GE_SDE_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43574; EPIMERASE-RELATED; 1.
DR   PANTHER; PTHR43574:SF86; UDP-GLUCOSE 4-EPIMERASE_UDP-SULFOQUINOVOSE SYNTHASE; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   PRINTS; PR01713; NUCEPIMERASE.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:GAM54710.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031671}.
FT   DOMAIN          4..230
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   334 AA;  37413 MW;  C595A5A5A232C620 CRC64;
     MKYLVTGAAG FIGSAVVERL TEAGHQVVGI DNMNDYYQVS LKEDRLKRIE HSSFTFKEID
     LADRDGIASL FEQEQFDIVI HLAAQAGVRY SIDNPLAYAD SNLVGHLTIL EGCRHNKVKH
     LVYASSSSVY GLNQKMPFDT SDSVDHPISL YAATKKSNEL MAHTYSHLYG VPTTGLRFFT
     VYGPWGRPDM ALFKFTKAIV NGDTIDVYNN GDMQRDFTYI DDIVEGIIRI QDVIPEPTAD
     WTVEQGSPAT SSAPYRVYNI GHGSPVKLME FIESLEDALG IEANKNFMLM QPGDVYATYA
     DTQDLFEATG YKPQVGVKEG VKAFADWYRE YYKL
//