ID A0A0B8NVP4_9VIBR Unreviewed; 542 AA.
AC A0A0B8NVP4;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Ascorbate-specific PTS system EIIC component {ECO:0000256|ARBA:ARBA00039702};
DE AltName: Full=Ascorbate-specific permease IIC component UlaA {ECO:0000256|ARBA:ARBA00042859};
GN ORFNames=JCM19231_5731 {ECO:0000313|EMBL:GAM58600.1};
OS Vibrio ishigakensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=1481914 {ECO:0000313|EMBL:GAM58600.1, ECO:0000313|Proteomes:UP000031671};
RN [1] {ECO:0000313|EMBL:GAM58600.1, ECO:0000313|Proteomes:UP000031671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 19231 {ECO:0000313|Proteomes:UP000031671};
RA Sawabe T., Meirelles P., Feng G., Sayaka M., Hattori M., Ohkuma M.;
RT "Vibrio sp. C1 JCM 19231 whole genome shotgun sequence.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GAM58600.1, ECO:0000313|Proteomes:UP000031671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 19231 {ECO:0000313|Proteomes:UP000031671};
RG NBRP consortium;
RA Sawabe T., Meirelles P., Feng G., Sayaka M., Hattori M., Ohkuma M.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC system (sugar PTS), a major carbohydrate active transport system,
CC catalyzes the phosphorylation of incoming sugar substrates
CC concomitantly with their translocation across the cell membrane. The
CC enzyme II UlaABC PTS system is involved in ascorbate transport.
CC {ECO:0000256|ARBA:ARBA00037387}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the UlaA family.
CC {ECO:0000256|ARBA:ARBA00038218}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAM58600.1}.
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DR EMBL; BBRZ01000094; GAM58600.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B8NVP4; -.
DR Proteomes; UP000031671; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR CDD; cd05563; PTS_IIB_ascorbate; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR InterPro; IPR036095; PTS_EIIB-like_sf.
DR InterPro; IPR013011; PTS_EIIB_2.
DR InterPro; IPR003501; PTS_EIIB_2/3.
DR InterPro; IPR004703; PTS_sugar-sp_permease.
DR PANTHER; PTHR33843; ASCORBATE-SPECIFIC PTS SYSTEM EIIC COMPONENT; 1.
DR PANTHER; PTHR33843:SF5; ASCORBATE-SPECIFIC PTS SYSTEM EIIC COMPONENT; 1.
DR Pfam; PF03611; EIIC-GAT; 1.
DR Pfam; PF02302; PTS_IIB; 1.
DR SUPFAM; SSF52794; PTS system IIB component-like; 1.
DR PROSITE; PS51099; PTS_EIIB_TYPE_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000031671};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 51..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 446..542
FT /note="PTS EIIB type-2"
FT /evidence="ECO:0000259|PROSITE:PS51099"
SQ SEQUENCE 542 AA; 59007 MW; 056C9E8E02DFB979 CRC64;
MIVQVGAGTL VAGFKPVIEK LSEIHGLTGS VIDPYTSMMA TMETMGENYS WVGYAVLLAL
GLNILLVAFR RFTGIRTIML TGHIMFQQAG LIAVFYFVLG ASMWETIIYS AILMALYWGI
SSNIMFKATE EVTGGAGFSI GHQQQFASWI ATKVAPKLGD KNDSVDHINL PKWLHIFHDS
IAATTIVMTV FFGIIMLSFG LDNLQEMAGG THWLIYIFET GLKFAVAIQV IVTGVRMFVA
ELSEAFNGIS ERLIPNAVLA IDCAAIYAYS PNAMVFGFMW GAVGQFVAVL ALLAFDAPIM
IIPGFIPMFF SNATIGVFAN HFGGWKAVMK ICFVMGIIEV VGSAWAIHIF AQSGTEFNGW
MGMADWALVF PPIMQGLSVS SMFFFVVVAL AGVYMYFASA KLRAEEDAEK AATMTAVTPE
GFEVEVKAER EATQVTSGQA VEQKPVRILV CCGSGQGSSM MCSKKIKSYL DKQGIPSTTS
NCAITDHKSR VDSFDIIVTS VALAEQVIEL PEGKFKLGVK NMIMPKTFAD DLVSIIKNNF
HK
//
