ID A0A0B9A5I3_BRELN Unreviewed; 837 AA.
AC A0A0B9A5I3;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Sarcosine dehydrogenase {ECO:0000313|EMBL:KHS50663.1};
DE EC=1.5.8.3 {ECO:0000313|EMBL:KHS50663.1};
GN ORFNames=AE0388_2735 {ECO:0000313|EMBL:KHS50663.1};
OS Brevibacterium linens.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Brevibacteriaceae;
OC Brevibacterium.
OX NCBI_TaxID=1703 {ECO:0000313|EMBL:KHS50663.1, ECO:0000313|Proteomes:UP000031488};
RN [1] {ECO:0000313|EMBL:KHS50663.1, ECO:0000313|Proteomes:UP000031488}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AE038-8 {ECO:0000313|EMBL:KHS50663.1,
RC ECO:0000313|Proteomes:UP000031488};
RA Maizel D., Utturkar S.M., Brown S.D., Ferrero M., Rosen B.P.;
RT "Draft Genome Sequence of Brevibacterium linens AE038-8.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHS50663.1}.
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DR EMBL; JTJZ01000022; KHS50663.1; -; Genomic_DNA.
DR RefSeq; WP_039211421.1; NZ_JTJZ01000022.1.
DR AlphaFoldDB; A0A0B9A5I3; -.
DR STRING; 1703.BLSMQ_0395; -.
DR PATRIC; fig|1703.6.peg.2680; -.
DR OrthoDB; 2055370at2; -.
DR Proteomes; UP000031488; Unassembled WGS sequence.
DR GO; GO:0008480; F:sarcosine dehydrogenase activity; IEA:UniProtKB-EC.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR13847:SF181; TRANSFERASE CAF17, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:KHS50663.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000031488}.
FT DOMAIN 10..370
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 373..428
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 434..708
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 760..820
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 837 AA; 91200 MW; EBFB6C88FABBBAF0 CRC64;
MASVPAQASV VVVGAGIVGN SLVHHLAELG WTDIVQVDKG PLPNPGGSTG HASNFIFPVD
HSREITDLTL DSVRQYKELG VFTESGGFEV ARTEERMEEL RRRMASARAW GIESSLVTPA
EVVEKVPFLD PEVILGAFWT PTVGVVDSVR AGTMMRESAE AKGALTVSPN TEVTGIDVED
GQIVAVHTTK GEIATNRILI ACGVWSPRIA AMAGAAIPLT PAVHQMISVG PVPQLAERPG
EISYPIVRDM DTFCYERQHG SDMEIGSYAH RPILHDPDEI PSIEAAKLSP TEMPFTDEDF
DPQLEQAVEL MPEVLSNPDV EIRYAINGLL SLTPDGAPIL GESPQVKGLW SAAAVWVKEG
PGVGRAVAEW MTNGLPEIDV QGADIARFHS HQRTRAHVKA RTSEAFNKTY GIVHPGEQWS
SDRDVRRSPM WLREADLGAV FFEAGGWERP QWFESNAGLL EEFGDAVMDR SNEWDSRWWS
PIINAEHLAM RQRAGLVDLS SFVIFDVFGP AALDAVQAIA LAQMDVAVGR VVYTPILDES
GGFRSDLTIM RLAHDRFRVV TGAAHGMVDV KWFADRLPDT GAQIADLTSS WTTIGLWGPR
ARDILGELTS ADVSHEGFKF GTARTIEIGS LEVLASRISY VGDLGWELYV PMESGLKLWD
MLMEAGHEHD LIPVGLGVYG TTGRIEKGYR AFGAELDSER SVIEVGMARP KVKSQDFIGK
SAHLRHREEE PKTVLCSLTV DDHTSASGEK RYMLGAEPIV SADGQPLVDG HGRPAYVTSA
GSAPSLGKHV LMAFLPPAEA VLGNRLQVVY MEEFYPVTVA SIDSTPLFDP DNECIRR
//
