ID A0A0B9ANR2_BRELN Unreviewed; 862 AA.
AC A0A0B9ANR2;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=AE0388_3032 {ECO:0000313|EMBL:KHS50960.1};
OS Brevibacterium linens.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Brevibacteriaceae;
OC Brevibacterium.
OX NCBI_TaxID=1703 {ECO:0000313|EMBL:KHS50960.1, ECO:0000313|Proteomes:UP000031488};
RN [1] {ECO:0000313|EMBL:KHS50960.1, ECO:0000313|Proteomes:UP000031488}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AE038-8 {ECO:0000313|EMBL:KHS50960.1,
RC ECO:0000313|Proteomes:UP000031488};
RA Maizel D., Utturkar S.M., Brown S.D., Ferrero M., Rosen B.P.;
RT "Draft Genome Sequence of Brevibacterium linens AE038-8.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHS50960.1}.
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DR EMBL; JTJZ01000022; KHS50960.1; -; Genomic_DNA.
DR RefSeq; WP_039211700.1; NZ_JTJZ01000022.1.
DR AlphaFoldDB; A0A0B9ANR2; -.
DR PATRIC; fig|1703.6.peg.2984; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000031488; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000031488};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 517..851
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 337..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 862 AA; 92104 MW; D5210C8F2686DC39 CRC64;
MTSSASSVPT SSHVIQPDVR VRGAREHNLR NVDLTVPRDA LVVFTGVSGS GKSSLAFGTL
YAESQRRYLE SVAPYARRLI DQAGVPDVDS ITGMPPAVAL QQQRGGRSAR SSVGSITTVS
SLVRMLFSRA GHYPVDQPML LAEEFSTNTV EGACPECHGI GRVFDVPEEK MVPDPTLTIR
ERAIDSWPKA WHGHQLRDVL VALGYDVDVP WKDLPREHRD WILYTEETPH MPVHSRLTLA
EAKEAIAAGA EPTYSGTFVG ARKYVLDTFA NTKSAGMKRR VAEFLSVETC PVCHGKKLKP
EALSVTIAGR DIAEFSALPL HELTTLLETE VAAAKAGMEA GEGSDAHDSD GGAHPSAEKS
AAFVRLGEGL VERLRPIRDL GLGYLSLGRT TPTLSGGELQ RLRLATQLTS DLFGVVYVLD
EPSAGLHPQD VDALMGILDG LKARGNSLFV VEHSVDIMRH ADWLVDIGPG AGERGGEVLF
SGPTAGLAEV EESVTRGYVF GDRGLEPHPP REPQGRLRLE GIRRNNIADA TVEVPLGVLT
AVTGVSGSGK SSLVSQALPV LVGDRLGAGT EASEPEPEGD DLLLVDESEE LAGTVTGDLT
GIRRVVSIDQ KPIGRTPRSN VATYTGLFDH VRRRFAETPE ARERGYKPGR FSFNVSGGRC
PTCEGEGSVM VELLFLPSVY TECPDCHGTR FQSSTLEVLW RGRNIAEILA MSVEEAHEFF
TGEFDIIRSL TALIDVGLGY LRLGQPATEL SGGEAQRVKL ASELQRSQRG DTLYVLDEPT
SGLHCADADR LVAHLQSLVD AGNTVVMVEL DMRVVAVADH VIELGPGAGR AGGQVVATGS
PAEVAATGAG PSATYLAAAL GQ
//
