ID A0A0C1F3V7_9FLAO Unreviewed; 1315 AA.
AC A0A0C1F3V7;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=OA85_06000 {ECO:0000313|EMBL:KIA87827.1};
OS Flavobacterium sp. AED.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1423323 {ECO:0000313|EMBL:KIA87827.1, ECO:0000313|Proteomes:UP000031403};
RN [1] {ECO:0000313|EMBL:KIA87827.1, ECO:0000313|Proteomes:UP000031403}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AED {ECO:0000313|EMBL:KIA87827.1,
RC ECO:0000313|Proteomes:UP000031403};
RA Gale A.N., Newman J.D.;
RT "Flavobacterium sp. AED Genome.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIA87827.1}.
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DR EMBL; JSYM01000001; KIA87827.1; -; Genomic_DNA.
DR RefSeq; WP_039109405.1; NZ_JSYM01000001.1.
DR STRING; 1423323.OA85_06000; -.
DR OrthoDB; 1522078at2; -.
DR Proteomes; UP000031403; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF07494; Reg_prop; 4.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 2.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KIA87827.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:KIA87827.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1315
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002132087"
FT TRANSMEM 764..786
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 822..1035
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1067..1182
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1214..1313
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT MOD_RES 1115
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1315 AA; 152254 MW; BCFBB32BF1C99DFC CRC64;
MRKFLFFCIF LILTIDSLQA QEYYFKHYQV EEGLSNNTVL SSLQDEDGFM WFGTKDGLNR
FDGYRFKTYR SNSDPIHSLG SNYIQSLHEY KGIIWVGTDK GLYKYDKKLD RFSILNEAIN
DRIAAIEHDN HGNIWFISGN ILYKYSTVKN ETTTFNPNKY FIATSITRDA KGEIWVSSLN
KLYHYSEESL SFETVPLNYN NPSYRITVIY ALDKNNILIG TQDHGVLSYN RINKSTSSLP
FATKDPLFVR QFKKNGKNEI WIASESGVYI YNIQTKKYIN LKKDFNDPFS ISDNAAYSIT
IDKENGVWIG TYFGGINYHQ KQYTQFKKYF PKNNQNSISG SAVREIHKDD NGDFWIGTED
AGLNKFNPKT QVFTSYKPNG SPGSVSYYNI HALLPRKENI WIGTFEHGLD VLDRKSGKVI
KHYNAGTEAG ALKSNFIFSF YKTRNKDLLV QTSVGIYKYN SINDNFDVLK NFPENMHYTS
FMEDNDGNYW AGTYRDGLLF YNSKNKKKEI FRYNYKDAKG ISNNSINSIF EDSKKNLWIA
TENGLNLFDK KTRTFTKFNT KKGFPSNVFY SILEDDKQNL WITTSKGLVQ FNPENNSIKI
YTTANGLLSD QFNYNSAYKD TNGDMYFGNL NGMISFNPKH FSKNKFAPKI FITSLQINNQ
EVQTNDKDSP IKKSISHVDE LELNHNQSSF NIEFAALNYT GAELTEYWYK LEDVNKDWVY
LERNNKVFFT ELSPGSYIFK VKSRNSFGVW SKEIAVKIKI LPPFWASTYA YLLYFMLICY
GLFMIIRYSN NLSQEKNDRK IKHLNDEKEK EIYQAKIEFF TNVAHEIKTP LTLIKSPLEK
LLKFEYQTPE IPQNLSIMKK NTSRLLKLVN ELLDFRKTEI GGLKLTFVEV NISALVRNMH
LRFSQLIEEK NIDFELELSD KDIYAFVDKE ALKKILSNLF NNAIKYSEKK VIVSLIRDEK
KLELIVKNDG KLIPSNLKDK IFEPFFRVDN MDTNSGTGIG LSLAHSLTQL HHGSLQLIFS
EPKMNVFEFI VPLHQEEEFM LYDEQTKETN NNENEIIEPE IKSEKTTILV VEDNEDLLNF
ITNELLSSYA VLKANNGETA LKIIHNENIA LVISDIEMPI MDGITLCKKI KTNLETSHIP
VILLTAKNSL KSQIDGLEVG ADSYVAKPFS MEYLKVQSSN LIENRKQIMN YYASSPLSHI
KSMAHNKTDE NFLKKLDEEI IKNIADQNLS VESLSEIMNM SRSTLYRKIK DISNMSPNEL
INLVRLKKAA ELLLNKDYKM YEIAEIVGYK SQTSFGRNFH KHFKMSPSDY ISMNK
//
