ID A0A0C1G8H4_9SPHI Unreviewed; 537 AA.
AC A0A0C1G8H4;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Peptidase S8 {ECO:0000313|EMBL:KIA96409.1};
GN ORFNames=OC25_01220 {ECO:0000313|EMBL:KIA96409.1};
OS Pedobacter kyungheensis.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=1069985 {ECO:0000313|EMBL:KIA96409.1, ECO:0000313|Proteomes:UP000031246};
RN [1] {ECO:0000313|EMBL:KIA96409.1, ECO:0000313|Proteomes:UP000031246}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KACC 16221 {ECO:0000313|EMBL:KIA96409.1,
RC ECO:0000313|Proteomes:UP000031246};
RA Anderson B.M., Newman J.D.;
RT "Pedobacter Kyungheensis.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIA96409.1}.
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DR EMBL; JSYN01000002; KIA96409.1; -; Genomic_DNA.
DR RefSeq; WP_039470904.1; NZ_JSYN01000002.1.
DR AlphaFoldDB; A0A0C1G8H4; -.
DR OrthoDB; 9798386at2; -.
DR Proteomes; UP000031246; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07483; Peptidases_S8_Subtilisin_Novo-like; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 2.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034080; Protease_P7-like_dom.
DR PANTHER; PTHR43399; SUBTILISIN-RELATED; 1.
DR PANTHER; PTHR43399:SF4; TK-SUBTILISIN; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..537
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002132432"
FT DOMAIN 60..488
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT ACT_SITE 67
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 282
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 451
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 537 AA; 58420 MW; 3B8BD22E0AC735E2 CRC64;
MNKSRIFSAL LGAALVSAVP TLVHAQKANW QNLDLKSDST FGISTEKAYK ELLKGKKSVK
VIVAVNDGGV EATHEDLKRI MWVNKKEIAG NGKDDDKNGY ADDINGWNFI GGPKGSVNFE
TLELTRLVRR DMARFANTTD ANVAEKDKKD WETFKAERAD LEKQLGEAKA NLAGISGFKN
ALDAVVKKIG KENPTAEDFK NFKPSTPIEG RIQSVLVKQL EEGSFKDFYE DQIKEGFDYY
TRQAEYNLNL DYNPRDIVGD NPDDVNEKFY GNNDVAGPDA MHGSHVAGII AADRTNKIGI
WGVADNVAIM GVRCTPNGDE RDKDVANGIR YAVDNGAKVI NMSFGKAYSW NKAIVNEAMK
YAASKDVLIV QAAGNENKDI DVENNYPNHK DLDEKTIASW ITVGASGPTD DETLKASFSN
FGKTQVDVFA PGVHIYSTVP GSKYKNLDGT SMASPVVAGL AGLIRSYYPK LTAAQVKEII
VKSVTKVNHN VTYAKGEEPG AEKVSVPFSD LCISGGIVNA YNALKLAATY SGKANAK
//
