ID A0A0C1H4L7_9RHOB Unreviewed; 564 AA.
AC A0A0C1H4L7;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Guanylate cyclase {ECO:0000313|EMBL:KIC46863.1};
GN ORFNames=RA28_03770 {ECO:0000313|EMBL:KIC46863.1};
OS Ruegeria sp. ANG-S4.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Ruegeria.
OX NCBI_TaxID=1577904 {ECO:0000313|EMBL:KIC46863.1, ECO:0000313|Proteomes:UP000031326};
RN [1] {ECO:0000313|Proteomes:UP000031326}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ANG-S4 {ECO:0000313|Proteomes:UP000031326};
RX PubMed=25755651; DOI=10.3389/fmicb.2015.00123;
RA Collins A.J., Fullmer M.S., Gogarten J.P., Nyholm S.V.;
RT "Comparative genomics of Roseobacter clade bacteria isolated from the
RT accessory nidamental gland of Euprymna scolopes.";
RL Front. Microbiol. 6:123-123(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIC46863.1}.
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DR EMBL; JWLK01000001; KIC46863.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C1H4L7; -.
DR STRING; 1577904.RA28_03770; -.
DR Proteomes; UP000031326; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR CDD; cd00207; fer2; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR034804; SQR/QFR_C/D.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF17; BLL5647 PROTEIN; 1.
DR Pfam; PF00111; Fer2; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF81343; Fumarate reductase respiratory complex transmembrane subunits; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000031326};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 257..352
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
FT DOMAIN 370..501
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 564 AA; 62225 MW; BCFC11641A49132F CRC64;
MNSLDNALWR GGWVTRLRIV SGLVLFIFAF FHFMNIGLGL FHTDLLHGMQ DGRKFVTRHN
LISLVLYIAL IIHAGLALYS LARRRTLRMP FSMALQAILG LLIPLQLIAH IVQTRYAHEI
YDVNDEMGYI IILMWPSTAI WMQSLLVLLV WVHGCIGLHM WLRLTGWWRT AVPYLIGFAV
FVPGFALAGV LTEGRRLWTD FADPFLREQY IEHYNWPSPD EFEALFGVTD TALIVFWSLL
ALTGFIYLGR KLWRRRHSVR VRYVNGPEVV SEKGMTLLEM SQANGIPHTA LCGGKGRCTT
CRVVVEEGAD HLPAPGDVEA RSLAAVGAPE GTRLACQMRP TGPLTVFRVF RPDGGRDRAH
ASQGQERQLA VLFLDMRGFT ARTTGQLPYD IVFLLNRFFD AIVPAITAQG GTVDKYMGDG
LLAMFETRDA ASSALAGLHA AAGVGTALER FNRQLEAEGS PAIRIGMGLH LGDLVLGEIG
AARHAPRTII GDAVNVASRL EAETKALGVE LLVSQAVLSA AGLRTAPEEL RNFELRGVSA
PVPALLVEHA AQLESRINPE EQIA
//
