ID A0A0C1JCR1_9RHOB Unreviewed; 758 AA.
AC A0A0C1JCR1;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=thiol oxidase {ECO:0000256|ARBA:ARBA00012512};
DE EC=1.8.3.2 {ECO:0000256|ARBA:ARBA00012512};
GN ORFNames=RA28_09825 {ECO:0000313|EMBL:KIC46096.1};
OS Ruegeria sp. ANG-S4.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Ruegeria.
OX NCBI_TaxID=1577904 {ECO:0000313|EMBL:KIC46096.1, ECO:0000313|Proteomes:UP000031326};
RN [1] {ECO:0000313|Proteomes:UP000031326}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ANG-S4 {ECO:0000313|Proteomes:UP000031326};
RX PubMed=25755651; DOI=10.3389/fmicb.2015.00123;
RA Collins A.J., Fullmer M.S., Gogarten J.P., Nyholm S.V.;
RT "Comparative genomics of Roseobacter clade bacteria isolated from the
RT accessory nidamental gland of Euprymna scolopes.";
RL Front. Microbiol. 6:123-123(2015).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIC46096.1}.
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DR EMBL; JWLK01000002; KIC46096.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C1JCR1; -.
DR STRING; 1577904.RA28_09825; -.
DR Proteomes; UP000031326; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016972; F:thiol oxidase activity; IEA:UniProtKB-EC.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 1.20.120.310; ERV/ALR sulfhydryl oxidase domain; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR036774; ERV/ALR_sulphydryl_oxid_sf.
DR InterPro; IPR017905; ERV/ALR_sulphydryl_oxidase.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF69000; FAD-dependent thiol oxidase; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS51324; ERV_ALR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000031326}.
FT DOMAIN 107..142
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 507..645
FT /note="ERV/ALR sulfhydryl oxidase"
FT /evidence="ECO:0000259|PROSITE:PS51324"
FT REGION 161..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 758 AA; 85736 MW; 75F63487D6EBE511 CRC64;
MSRPIKIEEI ERLWDQIASG RDVVGFEDLA KALSGLGNQQ ATDHLDLIAD EYDQVDGITR
QQFLATLASL TGDLTSRVSI AFDVFDANGD RKITHDELRD VLLAFGIAED LTDHFFAAAD
KDGDGAISFS EFQAATSNAE GRHPLRYRDV HPSLMAPAPT ETVTSVQFSK NPQSAPQGKD
RRRGEGTSRL QMQIGLFRLL QGAAYRSFRE NFAANYETHL AAKTMPYTIT EFARYTERAI
ELYKALGVVE PACFEVLDAV PLSLRQELIK LDDRISTWAS IEKSMEMSRA AAEMDAERTD
RARTHHVFDA LVECALTLRR KNLTVADLSD GALDLHEVKR LRSLDLHQPP PSTKGGQDGD
NADYLAAWNG VILETAGEEI DGAMMPNAYW YQEFMPKLLA ACSVATADDI VANTMPDEAD
LDEWFHEARA SGEFHPFAEA EMDQFATCEP SQKLMIKQAW RLTRHYLNGI QKRRERLEFG
RDSGSLSQYV AFLDVYLGRS DVRDADMRLS FPYFIGPSTW RFLHTTAEII CHRDVEDQPK
LIALFKSFFR SFAAMYPCPY CRYHLNRYVV QNREVEYYPL EYLVLGCDQR KNGFEASIDN
KLDTISDGPS LRLFLWKLHN AVSSSITRTE PWFHRDERAF YASRYWPSLS EEVACARAFG
ETEVPINRLS HFSGMLTPVG RLASLRGRWR GMHMMTGSAN LAQLVSDAES SVRDLEDALA
AGEFLEKTYR FDPSFEDNAP HFTPEEEAYS RSGLFVEA
//
