ID A0A0C1JEJ5_9RHOB Unreviewed; 633 AA.
AC A0A0C1JEJ5;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Propionyl-CoA synthetase {ECO:0000313|EMBL:KIC45857.1};
DE EC=6.2.1.17 {ECO:0000313|EMBL:KIC45857.1};
GN Name=prpE {ECO:0000313|EMBL:KIC45857.1};
GN ORFNames=RA28_09270 {ECO:0000313|EMBL:KIC45857.1};
OS Ruegeria sp. ANG-S4.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Ruegeria.
OX NCBI_TaxID=1577904 {ECO:0000313|EMBL:KIC45857.1, ECO:0000313|Proteomes:UP000031326};
RN [1] {ECO:0000313|Proteomes:UP000031326}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ANG-S4 {ECO:0000313|Proteomes:UP000031326};
RX PubMed=25755651; DOI=10.3389/fmicb.2015.00123;
RA Collins A.J., Fullmer M.S., Gogarten J.P., Nyholm S.V.;
RT "Comparative genomics of Roseobacter clade bacteria isolated from the
RT accessory nidamental gland of Euprymna scolopes.";
RL Front. Microbiol. 6:123-123(2015).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIC45857.1}.
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DR EMBL; JWLK01000002; KIC45857.1; -; Genomic_DNA.
DR RefSeq; WP_039527099.1; NZ_JWLK01000002.1.
DR AlphaFoldDB; A0A0C1JEJ5; -.
DR STRING; 1577904.RA28_09270; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000031326; Unassembled WGS sequence.
DR GO; GO:0050218; F:propionate-CoA ligase activity; IEA:UniProtKB-EC.
DR CDD; cd05967; PrpE; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Ligase {ECO:0000313|EMBL:KIC45857.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000031326}.
FT DOMAIN 3..57
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 64..448
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 514..592
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 633 AA; 68649 MW; 9FF6B6C4223DB4B6 CRC64;
MSYADAYASW QADPEAFWGK AAEQIDWFKP AEKVFDPEMG VYGRWFAGAT CNTCWNCVDR
HVEAGNGERT ALIYDSPVTD TVQAFSFSEL QAEVGALASV MRAYGVGKGD RVVIYMPMVP
QAVFAMLACA RLGAIHSVVF GGFAPHELAT RINDAAPKMI ISASCGIEPG RIVHYKPLLD
AAIAEAATKP DHCLILQRDM ERADLIPGRD LDYAELVSQA KAAGETTECV PVAATDPLYI
LYTSGTTGQP KGVVRDNGGH MVALKWTMEH HYGMNPGEVF WAASDVGWVV GHSYICYGPL
LHGCATVVYE GKPVGTPDAG AFWRVIQDHQ VAALFTAPTA FRAIKKEDPR GLLIEQYNLS
KFRTQFLAGE RSDPATIQWA EEKLKRPVID HWWQTETGWA MSGNPVGLGQ LPVKYGSPGK
PMPGYDIRVL DDEGHEVEPG TLGNIVCKLP LPPSGFPTLW NAPERFLTSY MNEFPGFYAT
SDAGIIDEDG YVFIMARTDD IINVAGHRLS TGAMEEVIGA HPDIAECAVV GAADAMKGQM
PLGFYVTNDG ANRDAAELEK ELVALMREQI GAVAAFKTAI PVKRLPKTRS GKVLRGTMQK
IADSAAFKMP AAIDDPAILD EISDALKGRG LLS
//
