ID A0A0C1JK42_9BACT Unreviewed; 521 AA.
AC A0A0C1JK42;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Putative serine/threonine-protein kinase PknB {ECO:0000313|EMBL:KIC71655.1};
DE EC=2.7.11.1 {ECO:0000313|EMBL:KIC71655.1};
GN Name=pknB {ECO:0000313|EMBL:KIC71655.1};
GN ORFNames=DB41_AS00090 {ECO:0000313|EMBL:KIC71655.1};
OS Neochlamydia sp. TUME1.
OC Bacteria; Chlamydiota; Chlamydiia; Parachlamydiales; Parachlamydiaceae;
OC Neochlamydia.
OX NCBI_TaxID=1478174 {ECO:0000313|EMBL:KIC71655.1, ECO:0000313|Proteomes:UP000031320};
RN [1] {ECO:0000313|EMBL:KIC71655.1, ECO:0000313|Proteomes:UP000031320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TUME1 {ECO:0000313|EMBL:KIC71655.1,
RC ECO:0000313|Proteomes:UP000031320};
RX PubMed=25069652; DOI=10.1093/molbev/msu227;
RA Domman D., Collingro A., Lagkouvardos I., Gehre L., Weinmaier T.,
RA Rattei T., Subtil A., Horn M.;
RT "Massive expansion of Ubiquitination-related gene families within the
RT Chlamydiae.";
RL Mol. Biol. Evol. 31:2890-2904(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIC71655.1}.
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DR EMBL; JRXI01000215; KIC71655.1; -; Genomic_DNA.
DR RefSeq; WP_052244120.1; NZ_JRXI01000215.1.
DR AlphaFoldDB; A0A0C1JK42; -.
DR PATRIC; fig|1478174.3.peg.2212; -.
DR Proteomes; UP000031320; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0010506; P:regulation of autophagy; IEA:InterPro.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR045269; Atg1-like.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR24348:SF22; NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE; 1.
DR PANTHER; PTHR24348; SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF07228; SpoIIE; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KIC71655.1};
KW Transferase {ECO:0000313|EMBL:KIC71655.1}.
FT DOMAIN 34..311
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 521 AA; 58981 MW; CD318DE3BD010495 CRC64;
MTASESHQRP TLPAMPSDKE SFLSLPLPKK IGPYKIEALL EKGGMSILYL GTHPETNEPT
TIKVLSPKFV SNPEIVERFL KEAEIIALAD HPNIVKLYGQ GKWAGGLYIA MEFIQGISLR
QYILQTPISL RRALEIIIDI SYALCHLHTH GVIHRDLKPE NILVTESDVI KVIDFGIAQL
LKESSSDISK QPRMIGTPIY MSPEQQQQPD SVSFPSDIYS LGIIAYELML GKLSQGHIHL
SLMPKGMQKI LVKALQPEVR DRYQDIVDFI AAVSGYLNSE SFEKDKIVKD YLSELSESLR
RTQAVLSHDK APQWNGVHVK VTASNTHAIA GVYYDFLEIN PGSYGIAFAE SSLNYSDGMV
VCSIFRGMLK ALYKRVTDLK ELAYLLNQLI IEDGLDKSLK FNYLTIDTQQ NKVQYLICGH
SYLWARPHHK TPFKVICENP PLGSDPHSQF QIQQVDWKSN DSYILSNTNL EMSEKELLEI
WQSAEKLNPP LWMEIFLRRK RAMHKILSEK AITFIAIQSL A
//
