ID A0A0C1QVF6_9CYAN Unreviewed; 371 AA.
AC A0A0C1QVF6;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN Name=wecB {ECO:0000313|EMBL:KAF3888724.1};
GN ORFNames=DA73_0242950 {ECO:0000313|EMBL:KIE07768.1}, DA73_0400027000
GN {ECO:0000313|EMBL:KAF3888724.1};
OS Tolypothrix bouteillei VB521301.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Tolypothrichaceae;
OC Tolypothrix.
OX NCBI_TaxID=1479485 {ECO:0000313|EMBL:KIE07768.1};
RN [1] {ECO:0000313|EMBL:KIE07768.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VB521301 {ECO:0000313|EMBL:KIE07768.1};
RX PubMed=25700407;
RA Chandrababunaidu M.M., Singh D., Sen D., Bhan S., Das S., Gupta A.,
RA Adhikary S.P., Tripathy S.;
RT "Draft Genome Sequence of Tolypothrix boutellei Strain VB521301.";
RL Genome Announc. 3:e00001-15(2015).
RN [2] {ECO:0000313|EMBL:KAF3888724.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VB521301 {ECO:0000313|EMBL:KAF3888724.1};
RA Sarangi A.N., Mukherjee M., Ghosh S., Singh D., Das A., Kant S., Prusty A.,
RA Tripathy S.;
RT "Improved Assembly of Tolypothrix boutellei genome.";
RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIE07768.1}.
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DR EMBL; JHEG04000001; KAF3888724.1; -; Genomic_DNA.
DR EMBL; JHEG02000059; KIE07768.1; -; Genomic_DNA.
DR RefSeq; WP_038076449.1; NZ_JHEG04000001.1.
DR AlphaFoldDB; A0A0C1QVF6; -.
DR STRING; 1479485.DA73_0242950; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000029738; Unassembled WGS sequence.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000029738}.
FT DOMAIN 27..363
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 371 AA; 40858 MW; 495BA3D262262A90 CRC64;
MAKKQIHIIL GTRPEAIKLA PVIQVFQNSS TVDTKVILTG QHREMVEQVM QLFDLKANDD
LEIMQPKQSL SDITCRSLRG LEELFQQNKP DLAIVQGDTT TAFAATLAAF YQKIPVGHVE
AGLRTDDLLN PYPEEANRRL ISQLTQLHFA PTPLAVENLE RSGVLGKVCL TGNTVIDALL
SVAAREPACY VPGLEWSQYR VLLATVHRRE NWGEPLQDIA QGFLQILDKI PDTALLLPLH
RNPTVREPLQ AWLGNHPRIF LTEPLDYAEL VGAIMRSHLV LTDSGGLQEE APSLGKPVLV
LRETTERPEA VTAGTAKLVG TASQNICTHA VELLTNPTAY ETMANAINPF GDGQAAKRIL
QIVQNYFGMS S
//
