ID A0A0C1R338_9CLOT Unreviewed; 220 AA.
AC A0A0C1R338;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Diphthamide synthase domain-containing protein {ECO:0000259|Pfam:PF01902};
GN ORFNames=U732_3661 {ECO:0000313|EMBL:KIE47927.1};
OS Clostridium argentinense CDC 2741.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1418104 {ECO:0000313|EMBL:KIE47927.1, ECO:0000313|Proteomes:UP000031366};
RN [1] {ECO:0000313|EMBL:KIE47927.1, ECO:0000313|Proteomes:UP000031366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 2741 {ECO:0000313|EMBL:KIE47927.1,
RC ECO:0000313|Proteomes:UP000031366};
RX PubMed=25489752; DOI=10.1016/j.meegid.2014.12.002;
RA Smith T.J., Hill K.K., Xie G., Foley B.T., Williamson C.H., Foster J.T.,
RA Johnson S.L., Chertkov O., Teshima H., Gibbons H.S., Johnsky L.A.,
RA Karavis M.A., Smith L.A.;
RT "Genomic sequences of six botulinum neurotoxin-producing strains
RT representing three clostridial species illustrate the mobility and
RT diversity of botulinum neurotoxin genes.";
RL Infect. Genet. Evol. 30:102-113(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIE47927.1}.
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DR EMBL; AYSO01000013; KIE47927.1; -; Genomic_DNA.
DR RefSeq; WP_039630891.1; NZ_AYSO01000013.1.
DR AlphaFoldDB; A0A0C1R338; -.
DR STRING; 29341.RSJ17_17660; -.
DR OrthoDB; 3572539at2; -.
DR Proteomes; UP000031366; Unassembled WGS sequence.
DR CDD; cd01994; Alpha_ANH_like_IV; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.90.1490.10; putative n-type atp pyrophosphatase, domain 2; 1.
DR InterPro; IPR002761; Diphthami_syn_dom.
DR InterPro; IPR030662; DPH6/MJ0570.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00290; MJ0570_dom; 1.
DR PANTHER; PTHR12196:SF2; DIPHTHINE--AMMONIA LIGASE; 1.
DR PANTHER; PTHR12196; DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN; 1.
DR Pfam; PF01902; Diphthami_syn_2; 1.
DR PIRSF; PIRSF039123; Diphthamide_synthase; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000031366}.
FT DOMAIN 6..211
FT /note="Diphthamide synthase"
FT /evidence="ECO:0000259|Pfam:PF01902"
SQ SEQUENCE 220 AA; 24673 MW; A158684BB5CF985E CRC64;
MSKKIKFAAS YSGGKDGMLA LYRAIESGYE PVSLLTTYNE SANRSWFHGV PVEVLNKVSQ
LIDIPLELVK TGAGDDYAKD FEKALLKLKD SGVNACVFGD IDIQAHYDWC DSRCKAAKIR
SIFPLWNESR KELVYEFIES GFKAVITIVD SSRLSEKFLG KTLTKELIKE IVAEGADICG
ENGEYHTFVY DGPLFKEPVN FKFDEIIRNG NYSVLPLSLE
//
