ID A0A0C1RK15_9ACTN Unreviewed; 665 AA.
AC A0A0C1RK15;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=MB53_03835 {ECO:0000313|EMBL:KIE50981.1};
OS marine actinobacterium MedAcidi-G2A.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1550400 {ECO:0000313|EMBL:KIE50981.1, ECO:0000313|Proteomes:UP000031257};
RN [1] {ECO:0000313|EMBL:KIE50981.1, ECO:0000313|Proteomes:UP000031257}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mizuno C.M., Rodriguez-Valera F., Ghai R.;
RT "Novel reconstructed genomes of marine planktonic Acidimicrobiales.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIE50981.1}.
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DR EMBL; JUEN01000014; KIE50981.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C1RK15; -.
DR STRING; 1550400.MB53_03835; -.
DR Proteomes; UP000031257; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 33..85
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 89..493
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 547..625
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 665 AA; 73997 MW; 7A620CC598429833 CRC64;
MADKQAIEEF YVENRTFPPL TDFADSALIN DDSLYEEANA NFEAFWARQS RELLTWEKDF
STILEWDLPY AKWFSDGELN ISYNCLDRHV ENGKGDKIAF HWEGEPGDTK AITYSELLSE
VSKFANVLKN FGLERGDTVA IYMPMILELP IAMLACARVG VVHSVIFGGF SPDAIVDRCE
DAEAKLIITA DAGYRRGDPS PLKVNVDAAL ASGAPTVQNV VVVDRCNTPV EMQEGRDHWW
HNLMMNVSTN CPAEPMPAEQ LLYLLYTSGT TAKPKGIMHT SGGYLTQVAF THKHIFDLQP
ETDIYWCAAD IGWVTGHSYI VYGPLTNGCT SVMYEGTPDT PREDLREGED RQLWLKDRLW
DIIERYKVTQ FYTAPTAIRT FMKWGNEETQ NHDLSSLRVL GTVGEPINPE AWMWYHENIG
GASTPIVDTW WQTETGGHMI TPLPGVTTTK PGSACFTIPG VFAEVVDDEG KKVTQGGGYL
TITKPWPAML RGIWGDPKRY LETYWSTYKG KYFAGDGVKI DSDGYLWLLG RVDDVMNISG
HRISTAEVES ALVDHPSVAE AAVVGATDET TGQAIIGYVI LRGSYESSNE LRDEIRSHVA
EKLGPIARPK AVFLVPDLPK TRSGKIMRRL LRDVAEGRDL GDTTTLADAN VVTAIQDGAQ
NSDEN
//
