ID A0A0C1XE65_9ACTN Unreviewed; 822 AA.
AC A0A0C1XE65;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=beta-mannosidase {ECO:0000256|ARBA:ARBA00012754};
DE EC=3.2.1.25 {ECO:0000256|ARBA:ARBA00012754};
GN ORFNames=QR77_01790 {ECO:0000313|EMBL:KIF73068.1};
OS Streptomyces sp. 150FB.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1576605 {ECO:0000313|EMBL:KIF73068.1, ECO:0000313|Proteomes:UP000031584};
RN [1] {ECO:0000313|EMBL:KIF73068.1, ECO:0000313|Proteomes:UP000031584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=150FB {ECO:0000313|EMBL:KIF73068.1,
RC ECO:0000313|Proteomes:UP000031584};
RA Tarkka M.T., Feldhahn L., Kruger D., Buscot F., Wubet T.;
RT "Genome sequence of the mycoparasite antagonist Streptomyces sp. strain FB
RT 150.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-mannose residues
CC in beta-D-mannosides.; EC=3.2.1.25;
CC Evidence={ECO:0000256|ARBA:ARBA00000829};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIF73068.1}.
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DR EMBL; JTHL01000001; KIF73068.1; -; Genomic_DNA.
DR RefSeq; WP_040019343.1; NZ_JTHL01000001.1.
DR AlphaFoldDB; A0A0C1XE65; -.
DR STRING; 1576605.QR77_01790; -.
DR OrthoDB; 9758603at2; -.
DR Proteomes; UP000031584; Unassembled WGS sequence.
DR GO; GO:0004567; F:beta-mannosidase activity; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR43730; BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR43730:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000031584}.
FT DOMAIN 207..298
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 822 AA; 90944 MW; EA8D2219C67CD837 CRC64;
MTATDDFSRT SRTGVSTPLT SGWTLRHEGE DLPAAVPGCV HTDLLAAGRI PDPFQGRNEL
DVEWVGRADW TYDIVVNAQD THHERTDLVF EGLDTVAEIT LGGEVLGNTA NMHRSYRFDV
TGKLDGPSTA LAVRFTSAYT AADELRQSMG AREEAYPHPS AFVRKMACAF GWDWGPSLPT
AGIWKPARLE HWSTARLARV RPLVTVDGGT GRVEVRLDVA RTVPGAARAL TAEVRVADGR
TVSVPVAGDS ATVTTEVPEV ALWWPRGYGE QPLYPCEVTL LDENGAVLDT WSRRIGFRTV
VLDTPSDEHG TGFTFVINGE RVFARGVNWI PDDVFPSRVT SDRYRERLTQ AADAGVNLVR
VWGGGIFERD DFYDVCDELG LMVWQDFLFA CTTYPEEQPV RSEVEAEARE NVARLMPHAS
LVLWNGNNEN LWVYRLWNWE EKLAGDSWGE GYYLGLLPRV VAETDPTRPY WAGSPWSGSW
DHAPEDPAHG CTHLWDVWNT TDYTDYLDSV PRFVSEFGWQ APPAHTTFRD ALPGEVLAPD
SPGVLHHQKA DDGNGKLERG LARHFDVPTD FDTWHYLMQV NQARAVATGV EHWRSHWPVC
AGAIVWQLND CWPVSSWSAI DSAARLKPLW YELRRLYADR LLTVQRRDGL LTLCMVNQSA
DSWGSEVRLR RMDADGTLLA ETALPLAAAR NSVATVPIPA SLVPDDASGS EYVVADADGL
RALHVPVRDL VFAYPRPDFD ISLAPAPVEP DGPDGLGGDV LVRIEARTLL RDALLQADRL
APTATADQGL FTLLPGESLT VRVQGWPDPD PESARKALFT LG
//
