ID A0A0C1Y431_9ACTN Unreviewed; 392 AA.
AC A0A0C1Y431;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Tagatose-6-phosphate ketose isomerase {ECO:0000313|EMBL:KIF75312.1};
GN ORFNames=QR77_18075 {ECO:0000313|EMBL:KIF75312.1};
OS Streptomyces sp. 150FB.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1576605 {ECO:0000313|EMBL:KIF75312.1, ECO:0000313|Proteomes:UP000031584};
RN [1] {ECO:0000313|EMBL:KIF75312.1, ECO:0000313|Proteomes:UP000031584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=150FB {ECO:0000313|EMBL:KIF75312.1,
RC ECO:0000313|Proteomes:UP000031584};
RA Tarkka M.T., Feldhahn L., Kruger D., Buscot F., Wubet T.;
RT "Genome sequence of the mycoparasite antagonist Streptomyces sp. strain FB
RT 150.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-galactosamine 6-phosphate + H2O = D-tagatopyranose 1-
CC phosphate + NH4(+); Xref=Rhea:RHEA:47680, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:28938, ChEBI:CHEBI:71674, ChEBI:CHEBI:138150;
CC Evidence={ECO:0000256|ARBA:ARBA00029292};
CC -!- SIMILARITY: Belongs to the SIS family. AgaS subfamily.
CC {ECO:0000256|ARBA:ARBA00007748}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIF75312.1}.
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DR EMBL; JTHL01000001; KIF75312.1; -; Genomic_DNA.
DR RefSeq; WP_040022939.1; NZ_JTHL01000001.1.
DR AlphaFoldDB; A0A0C1Y431; -.
DR STRING; 1576605.QR77_18075; -.
DR OrthoDB; 9779207at2; -.
DR Proteomes; UP000031584; Unassembled WGS sequence.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR CDD; cd05010; SIS_AgaS_like; 1.
DR CDD; cd05008; SIS_GlmS_GlmD_1; 1.
DR InterPro; IPR035466; GlmS/AgaS_SIS.
DR InterPro; IPR035464; SIS_AgaS.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR014180; Sugar_isomerase_AgaS.
DR NCBIfam; TIGR02815; agaS_fam; 1.
DR PANTHER; PTHR32502:SF3; D-GALACTOSAMINE-6-PHOSPHATE DEAMINASE AGAS-RELATED; 1.
DR PANTHER; PTHR32502; N-ACETYLGALACTOSAMINE PERMEASE II COMPONENT-RELATED; 1.
DR Pfam; PF01380; SIS; 2.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51464; SIS; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Isomerase {ECO:0000313|EMBL:KIF75312.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000031584};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 46..206
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
FT DOMAIN 217..372
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
SQ SEQUENCE 392 AA; 40625 MW; 84F40782DB9CBB50 CRC64;
MTSPSSTPPT DDGAANTVRE IAQQPRLWRE VGQLVAASRD SLDTFLRPLT ARGDLRVVLT
GAGTSAYAGQ VLQAGLARRL GLRVDAVATT DLVADPRGCL AEDVPTLLVS FARSGDSPES
VAAADLADQV LTEVHHLVIT CNEQGALALN HADRPTSHVL LMPAAANDQG FAMTSSFTCM
TLAALLALGG GAYDGIAERL ADAAELILKD GAADRAIGDL VGRAPERIVY LGSGALKGLA
EESALKVLEL TGGTVVAVAD SSMGFRHGPK AVLNDRTVVV VYVSNDPYTR QYDEDIVAEL
RGNLPGGRVV TVAAGALRAS ATDPEAGADV GTWPLPGLDD VDDVALALPA VVYAQLIALR
ASLAGGIRPD QPFPSGEVNR VVRGVILHPL AR
//
