ID A0A0C2B9N0_9ACTN Unreviewed; 1357 AA.
AC A0A0C2B9N0;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
DE Flags: Fragment;
GN ORFNames=QR77_37895 {ECO:0000313|EMBL:KIF78035.1};
OS Streptomyces sp. 150FB.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1576605 {ECO:0000313|EMBL:KIF78035.1, ECO:0000313|Proteomes:UP000031584};
RN [1] {ECO:0000313|EMBL:KIF78035.1, ECO:0000313|Proteomes:UP000031584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=150FB {ECO:0000313|EMBL:KIF78035.1,
RC ECO:0000313|Proteomes:UP000031584};
RA Tarkka M.T., Feldhahn L., Kruger D., Buscot F., Wubet T.;
RT "Genome sequence of the mycoparasite antagonist Streptomyces sp. strain FB
RT 150.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIF78035.1}.
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DR EMBL; JTHL01000001; KIF78035.1; -; Genomic_DNA.
DR STRING; 1576605.QR77_37895; -.
DR OrthoDB; 2472181at2; -.
DR Proteomes; UP000031584; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR CDD; cd12117; A_NRPS_Srf_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR010060; NRPS_synth.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR NCBIfam; TIGR01720; NRPS-para261; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 3.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000031584}.
FT DOMAIN 777..851
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KIF78035.1"
SQ SEQUENCE 1357 AA; 145994 MW; BDA3418D014482EF CRC64;
FWKRTLRDLP EQLELPVDFP RPAVASHVGG SVRVSVPAGV HARLVELSRG SGATAFMVVQ
AALAVLLSKM GAGEDIPIGT PVAGRTDDAL DDLVGFFVNT LVLRADVSGD PSFREVLERV
RERDLAAFAH QDVPFERLVE ILNPTRSMAR HALFQVMLTF QNNTRPDLDL PGIHAEVEPL
KSAAARFDLS FNLGETHTDD GTPAGLEGEL NYRTDLFAEA TVEVLADRLV RVLEAVVADP
DQPVRAIDVL GEEERRRTLV AWNDTAHEVP EASLPELFRA QVTRTPDALA VISDGAELTY
AELDARAEEL AHGLNARGVG SRDRVALLLG RWIDQVSMTL ALTRVGATYV PLDNRSPAAR
LEFILGDTSS VAVVVDRETL ALIPEQNPYG IDVLAVDELP TGRPPAATGT APQVRPLDLA
YIMYTSGSTG RPKGVAVSHR NVVALVSDRY WERAAADRVL LHSSPSFDAS TYEMWGALLT
GATLVAPAGV AADIPELART MGESRVTVGL FNEGIFRLLA ESEPESFSSL RDVYVGGDTM
SRAAVRKVRG QASRMRLTNS YGPTEATLCV AHYALPSETD DWASIPIGRP LDNTRLYVLD
KGLKPVPPGV VGELYVAGEG LARGYVDRPD LTAERFVADP FGPAGARMYR TGDRAKWRRD
GILEFAGRTD DQVKVRGFRI EPGEIEAALE SYANVAQAVV IAREDRPGDK RLVAYLVAAT
GARIDADATR LRLAEVLPDY MIPAAFVRVD ALPLGATGKL DRSALPAPDY SGGGRQAPRT
EKERVLCEVF AEVLGVDQVS ADDNFFAMGG DSIVSIQLVA KARAAGLIVT PRSVFERKTV
EALAAVAVES DERTAAGEDL GVGPVPLTPV MHQLRERGGS VDRFSQSVTL VAPAGLDRDD
LTAAVQALTN HHDLLRARLN TTSADGAWQL EVLPPEALSA ASCVSRVEVA GIEGVELRQA
VAEQEDEARS FLSPSDGRML RVVWLDAGPR RHGRLVVTVH HLAVDAVSWR ILVPDLVAAW
QDIVSGRKPE LQPVYTSFRR WADHSSAEAE RRVGELPLWE GVVADAGGAL SGFARSLDPA
HDTWGTARSV TVTLPADLTS ALLTSLPDAF NCGPDSVLLA AFLLAVGASD AQRQGSEPAV
VVDVERHGRE QVSPALDVSR TVGWFTSVAP VRLDLKSVSN GRTTVENDAE AALKHVKEQL
RAAPDNGFGY GMLRYLNPRT AERLSRFPEP GILFNYLGRI PVPAGGETPE EPWSVVGDGE
VGAGADPRMA MAYSLTINAV ARETAEGSEL LTTWAWPGRM WDEEGVRGLA EAYTHALTSL
AALAEAPGVG GLTPSDVSLL TLSQDEIDEF ELGEIED
//
