ID A0A0C2BAR4_9ACTN Unreviewed; 278 AA.
AC A0A0C2BAR4;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=RNA polymerase sigma factor {ECO:0000256|RuleBase:RU362124};
GN ORFNames=QR77_30355 {ECO:0000313|EMBL:KIF76999.1};
OS Streptomyces sp. 150FB.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1576605 {ECO:0000313|EMBL:KIF76999.1, ECO:0000313|Proteomes:UP000031584};
RN [1] {ECO:0000313|EMBL:KIF76999.1, ECO:0000313|Proteomes:UP000031584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=150FB {ECO:0000313|EMBL:KIF76999.1,
RC ECO:0000313|Proteomes:UP000031584};
RA Tarkka M.T., Feldhahn L., Kruger D., Buscot F., Wubet T.;
RT "Genome sequence of the mycoparasite antagonist Streptomyces sp. strain FB
RT 150.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. {ECO:0000256|RuleBase:RU362124}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family.
CC {ECO:0000256|RuleBase:RU362124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIF76999.1}.
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DR EMBL; JTHL01000001; KIF76999.1; -; Genomic_DNA.
DR RefSeq; WP_040025196.1; NZ_JTHL01000001.1.
DR AlphaFoldDB; A0A0C2BAR4; -.
DR STRING; 1576605.QR77_30355; -.
DR OrthoDB; 9799825at2; -.
DR Proteomes; UP000031584; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR CDD; cd06171; Sigma70_r4; 1.
DR Gene3D; 1.10.1740.10; -; 1.
DR Gene3D; 1.20.140.160; -; 1.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR000943; RNA_pol_sigma70.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR007624; RNA_pol_sigma70_r3.
DR InterPro; IPR007630; RNA_pol_sigma70_r4.
DR InterPro; IPR012845; RNA_pol_sigma_FliA_WhiG.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR NCBIfam; TIGR02479; FliA_WhiG; 1.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30385:SF7; RNA POLYMERASE SIGMA FACTOR FLIA; 1.
DR PANTHER; PTHR30385; SIGMA FACTOR F FLAGELLAR; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF04539; Sigma70_r3; 1.
DR Pfam; PF04545; Sigma70_r4; 1.
DR PIRSF; PIRSF000770; RNA_pol_sigma-SigE/K; 1.
DR PRINTS; PR00046; SIGMA70FCT.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2.
DR PROSITE; PS00715; SIGMA70_1; 1.
DR PROSITE; PS00716; SIGMA70_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU362124};
KW Reference proteome {ECO:0000313|Proteomes:UP000031584};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082,
KW ECO:0000256|RuleBase:RU362124};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU362124};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU362124}.
FT DOMAIN 75..88
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00715"
FT DOMAIN 243..269
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00716"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 278 AA; 30814 MW; D324EE52EEA9813D CRC64;
MPQHTSGSDR AAAPPAAREA VRPPAPSSLD ELWRSYKTTG DERLREQLIL HYSPLVKYVA
GRVSVGLPPN VEQADFVSSG VFGLIDAIEK FDIERSIKFE TYAITRIRGA MIDELRALDW
IPRSVRQKAR AVERAYATLE ARLRRTPSEV EVASEMDITL EELHAVFSQL SLANVVALEE
LLHVGGEGGD RLSLMDTLED TAADNPVEVA EGRELRRLLA RAINTLPDRE KTVVTLYYYE
GLTLAEIGNV LGVTESRVSQ IHTKSVLQLR GKLADVGR
//
