ID A0A0C2BIT6_9ACTN Unreviewed; 572 AA.
AC A0A0C2BIT6;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=AMP-dependent synthetase/ligase domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=QR77_37905 {ECO:0000313|EMBL:KIF78036.1};
OS Streptomyces sp. 150FB.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1576605 {ECO:0000313|EMBL:KIF78036.1, ECO:0000313|Proteomes:UP000031584};
RN [1] {ECO:0000313|EMBL:KIF78036.1, ECO:0000313|Proteomes:UP000031584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=150FB {ECO:0000313|EMBL:KIF78036.1,
RC ECO:0000313|Proteomes:UP000031584};
RA Tarkka M.T., Feldhahn L., Kruger D., Buscot F., Wubet T.;
RT "Genome sequence of the mycoparasite antagonist Streptomyces sp. strain FB
RT 150.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIF78036.1}.
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DR EMBL; JTHL01000001; KIF78036.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C2BIT6; -.
DR STRING; 1576605.QR77_37905; -.
DR Proteomes; UP000031584; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:UniProt.
DR CDD; cd17646; A_NRPS_AB3403-like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR001242; Condensatn.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR44845:SF6; BETA-ALANINE-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR44845; CARRIER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Reference proteome {ECO:0000313|Proteomes:UP000031584}.
FT DOMAIN 2..91
FT /note="Condensation"
FT /evidence="ECO:0000259|Pfam:PF00668"
FT DOMAIN 110..465
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 524..561
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT NON_TER 572
FT /evidence="ECO:0000313|EMBL:KIF78036.1"
SQ SEQUENCE 572 AA; 61734 MW; F534BA1A1224FAA0 CRC64;
MEEEAFAQAT STLRLSHTET HDATHYPLSL MVMPGSELHL RLDYRPDTFT STAVQDLAER
LIRILESFVA DTGRPVREID VLGEDERQRI LRGWNSTAHE VRETTLPELF EEQVARTPEG
VAVVSGGAEL SYAELNARVN SLARYLVSRG AGPERSVAVA MPRSLDLVVG LLAVVKTGAA
YVPVDPEYPS DRVAYMLQDA DPVLIITNTD TAQSLPAESS TGASRVVLDE GIVQARLRDQ
GTTNPADDEL LGSLLPQHPA YVIYTSGSTG RPKGVAVPHS AIVNRLLWMQ SVYSLKTTDR
VLQKTSMAFD VSVWEFFWPL IVGAGMVVAS AGEHKDPAAL AELIRREKVT TAHFVPSMLN
AFLQDPLAVP CEPLERVICS GEALSTDLKN RALSTLGASV HNLYGPTEAA VDVTFWECGA
DEETVPIGRP VWNTRVYVLD AGLSPVAVGV AGELYVAGAQ LARGYVGRAG LTGERFVADP
FGPVGSRMYR TGDLVKWAAG GVLEFVGRAD AQVKVRGFRI EPGEVEAALV GHQEVAQAAV
VVREDEPGEK RLVAYVVLVE SSTLDGSDLR GL
//
