ID A0A0C2E1A3_9BILA Unreviewed; 569 AA.
AC A0A0C2E1A3;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Metallo-beta-lactamase domain protein {ECO:0000313|EMBL:KIH69127.1};
GN ORFNames=ANCDUO_00539 {ECO:0000313|EMBL:KIH69127.1};
OS Ancylostoma duodenale.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=51022 {ECO:0000313|EMBL:KIH69127.1, ECO:0000313|Proteomes:UP000054047};
RN [1] {ECO:0000313|EMBL:KIH69127.1, ECO:0000313|Proteomes:UP000054047}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Zhejiang {ECO:0000313|EMBL:KIH69127.1,
RC ECO:0000313|Proteomes:UP000054047};
RA Mitreva M.;
RT "Draft genome of the parsitic nematode Ancylostoma duodenale.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily. RNA-
CC metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
CC {ECO:0000256|ARBA:ARBA00007093}.
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DR EMBL; KN726216; KIH69127.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C2E1A3; -.
DR Proteomes; UP000054047; Unassembled WGS sequence.
DR CDD; cd16291; INTS11-like_MBL-fold; 1.
DR Gene3D; 3.40.50.10890; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR022712; Beta_Casp.
DR InterPro; IPR041897; INTS11-like_MBL-fold.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11203:SF37; INTEGRATOR COMPLEX SUBUNIT 11; 1.
DR Pfam; PF10996; Beta-Casp; 1.
DR Pfam; PF16661; Lactamase_B_6; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM01027; Beta-Casp; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054047}.
FT DOMAIN 18..238
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT DOMAIN 258..376
FT /note="Beta-Casp"
FT /evidence="ECO:0000259|SMART:SM01027"
SQ SEQUENCE 569 AA; 63748 MW; F76098D4B61EBF83 CRC64;
MLVVPIQIVP LGAGQDVGRS CILVTIGGKN VMLDCGMHMG YQDERRFPDF STSAKPILFC
RYIGGGGKLN DYLTCVIVSH FHLDHCGSLP HMSEIVGFDG PIYMTYPTKA IAPVLLEDYR
KVQTEFRGDT NFFTSANIKA CMKKVIAVNL HETIQVDSEL SIRAFYAGHV LGAAMFEIRV
GHQSVLYTGD YNMTPDRHLG AARVLPGLRP DCLISESTYA TTIRDSKRAR ERDFLRKVHD
RVMGGGKVLI PVFALGRAQE LCILLESYWE RMDLKVPIYF SQGLAERANQ YYRLFINWTN
EKIKRTFVER NMFDFKHIKP LDKGYEEMPG AMVLFSTPGM LHGGQSLKVF RKWCHDPRNM
IIMPGYCVAG TVGAKVIGGM KKIEIEGKMH DINLGVEYMS FSAHADAKGI MQLIRDCQPR
TVMFVHGEAA KMEFLKGKVE KEFRIPVLMP ANGESVVIPG IATLEVDVPH DIVQRCIELD
PTPSKKACPF SACLVMDKQN GLEVISCEAA ASRLQMGLHT ITLSQLIKSR TAVDWRALSE
ALTIHDSHLQ HKKVRIILFA YNTRQPSAA
//
