ID A0A0C2GSU4_9BILA Unreviewed; 336 AA.
AC A0A0C2GSU4;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DNA polymerase delta catalytic subunit {ECO:0000256|ARBA:ARBA00024411};
GN ORFNames=ANCDUO_07652 {ECO:0000313|EMBL:KIH62069.1};
OS Ancylostoma duodenale.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=51022 {ECO:0000313|EMBL:KIH62069.1, ECO:0000313|Proteomes:UP000054047};
RN [1] {ECO:0000313|EMBL:KIH62069.1, ECO:0000313|Proteomes:UP000054047}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Zhejiang {ECO:0000313|EMBL:KIH62069.1,
RC ECO:0000313|Proteomes:UP000054047};
RA Mitreva M.;
RT "Draft genome of the parsitic nematode Ancylostoma duodenale.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN729618; KIH62069.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C2GSU4; -.
DR Proteomes; UP000054047; Unassembled WGS sequence.
DR GO; GO:0043625; C:delta DNA polymerase complex; IEA:UniProt.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 2.40.50.730; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR006133; DNA-dir_DNA_pol_B_exonuc.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10322; DNA POLYMERASE CATALYTIC SUBUNIT; 1.
DR PANTHER; PTHR10322:SF23; DNA POLYMERASE DELTA CATALYTIC SUBUNIT; 1.
DR Pfam; PF03104; DNA_pol_B_exo1; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000313|EMBL:KIH62069.1};
KW Hydrolase {ECO:0000313|EMBL:KIH62069.1};
KW Nuclease {ECO:0000313|EMBL:KIH62069.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054047}.
FT DOMAIN 140..335
FT /note="DNA-directed DNA polymerase family B exonuclease"
FT /evidence="ECO:0000259|Pfam:PF03104"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..31
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 336 AA; 36717 MW; 2D9696217366E332 CRC64;
MSPPKKRSST LPSAAAPKRR KRDEEPVSKM SPPKKRSSTL PSAAAPKRRK RDEEPASKGA
FESQLEQLSQ NSEAESCESS WDRADLEEGL GTTKAITLQA PENFAPEHLD VAQRNLNNAV
AVSLRRANSN LQMSSTVVDN LVRLSIVHGE NVYYYRGSEK KYPFIKVSGT TNALNKAKQE
LKNGGFSVGN GPVQVTTLYE ANIDAEVKFM AHSGIVGCGW VEIPAGKGVI HHSKAQSSRC
QLEVEVKLGD LIVHDPEGEW AAVAPIRTLS FDIECMGRRG IFPDANEDPV IQIANMVKVE
GESEPFIRNC FVLGTCSPVI GSDIIQCSTE KELLEK
//
