ID A0A0C2HDY8_9STAP Unreviewed; 728 AA.
AC A0A0C2HDY8;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:KIH71870.1};
GN ORFNames=SN16_00435 {ECO:0000313|EMBL:KIH71870.1};
OS Salinicoccus roseus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae; Salinicoccus.
OX NCBI_TaxID=45670 {ECO:0000313|EMBL:KIH71870.1, ECO:0000313|Proteomes:UP000031546};
RN [1] {ECO:0000313|EMBL:KIH71870.1, ECO:0000313|Proteomes:UP000031546}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W12 {ECO:0000313|EMBL:KIH71870.1,
RC ECO:0000313|Proteomes:UP000031546};
RA Wang H., Yu B.;
RT "Genome sequences of high lactate-tolerant strain Salinicoccus roseus W12
RT with industrial interest.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIH71870.1}.
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DR EMBL; JXII01000001; KIH71870.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C2HDY8; -.
DR STRING; 45670.SN16_00435; -.
DR Proteomes; UP000031546; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR Gene3D; 1.10.10.1230; Penicillin-binding protein, N-terminal non-catalytic domain, head sub-domain; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000031546}.
FT DOMAIN 65..304
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 370..678
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 728 AA; 81779 MW; DFF2598A3A4BA44E CRC64;
MKRAKTKSLE TINRQIMKSR INIIMLLVFL LCLLLIFRLG YLQIVQGDTY QEEVENAQFV
EINQSVPRGE IYDRNGNLLV GNASKKAVYF TRHRNMSSGE IMDVAVELSG YLDMETENLS
LRDKQDYLIN RYPDEVENLM AEEKTLLDNG NISQEQFNQE LYQRIDEEQV SSVLTEEDLN
TIAIYVEMVN ARELNPTVIK SEGVTEEEFA EINESLELLD GISTGMDWER DYPYGETLRT
VLGEVSSSEE GLPKELLDHY MARGYSRNDR VGKTYLEYQY ENVLRGEKEQ VKYSTDKSGE
IISQEVVKEG EPGDDLYLTV DIDLQLELEE LAEHHLTSLR SMAEEIQQRN SRSGEIDYTI
IPEYLNTVVL VVQDPNNGDV LAMVGKRLDD NGEVVDYHYG ALTSTYAVGS SVKGATVAAG
YQNDVIEAGE TLVDEPLEFA DGTTKSSFFN RDGKVAIDDQ EALMVSSNVY MMKIAMGIAG
MEYQPGMSLP SDVTEAGQTL RNGLSQFGLG VSTGIDLPNE ARSLKPEFNN NPSSYLDLSI
GQYDTYSALQ LSQYVSTIAN GGNRVGLHMA KEVREGDTNE EGAILQSFNG KVLNTVEFSP
AELAQIQNGF FDVFNTHDTS TDRYGTGWDA YHELEPKAAG KTGTAEAHFN GDPILNQTYT
GYAPHDDPDM AFSVIFPNMP YTVPFFPAQY LGRDVINKYY ELYHEEAAIA PYEYNTNDFY
SKLVYGSY
//
