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Database: UniProt
Entry: A0A0C2I6Q8_9PSED
LinkDB: A0A0C2I6Q8_9PSED
Original site: A0A0C2I6Q8_9PSED 
ID   A0A0C2I6Q8_9PSED        Unreviewed;       502 AA.
AC   A0A0C2I6Q8;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   16-JAN-2019, entry version 28.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=UCMB321_5527 {ECO:0000313|EMBL:KIH80802.1};
OS   Pseudomonas batumici.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=226910 {ECO:0000313|EMBL:KIH80802.1, ECO:0000313|Proteomes:UP000031535};
RN   [1] {ECO:0000313|EMBL:KIH80802.1, ECO:0000313|Proteomes:UP000031535}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCM B-321 {ECO:0000313|EMBL:KIH80802.1,
RC   ECO:0000313|Proteomes:UP000031535};
RA   Klochko V.V., Zelena L.B., Elena K.A., Reva O.N.;
RT   "Complete genome of Pseudomonas batumici UCM B-321 producer of the
RT   batumin antibiotic with strong antistaphilococcal and potential
RT   anticancer activity.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KIH80802.1}.
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DR   EMBL; JXDG01000070; KIH80802.1; -; Genomic_DNA.
DR   EnsemblBacteria; KIH80802; KIH80802; UCMB321_5527.
DR   PATRIC; fig|226910.6.peg.5515; -.
DR   Proteomes; UP000031535; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000031535};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      199    404       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      410    479       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     207    214       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   502 AA;  56360 MW;  2AC8DD7BA1291A31 CRC64;
     MELWQQCVEL LRDELPAQQF NTWIRPLQVE AEGDELRVYA PNRFVLDWVN EKYLGRLLEL
     LNEHGNGLAP VLSLLIGSKR SSAPRAAPNA PLAAAASQAM AASAPAPVAV NPPAQPAPTP
     KTAVEVSEEP SRDSFDPMAG ASSQQAPVRA EQRTVQVEGA LKHTSYLNRT FTFENFVEGK
     SNQLARAAAW QVADNPKHGY NPLFLYGGVG LGKTHLMHAV GNHLLKKNPN AKVVYLHSER
     FVADMVKALQ LNAINEFKRF YRSVDALLID DIQFFARKER SQEEFFHTFN ALLEGGQQVI
     LTSDRYPKEI EGLEERLKSR FGWGLTVAVE PPELETRVAI LMKKADQAKV ELPHDAAFFI
     AQRIRSNVRE LEGALKRVIA HSHFMGRDIT IELIRESLKD LLALQDKLVS VDNIQRTVAE
     YYKIKISDLL SKRRSRSVAR PRQVAMALSK ELTNHSLPEI GDVFGGRDHT TVLHACRKIN
     ELKESDADIR EDYKNLLRTL TT
//
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