ID A0A0C2JAG3_9ACTN Unreviewed; 461 AA.
AC A0A0C2JAG3;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Amino acid transporter {ECO:0000313|EMBL:KIH98456.1};
GN ORFNames=LP52_13620 {ECO:0000313|EMBL:KIH98456.1};
OS Streptomonospora alba.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Streptomonospora.
OX NCBI_TaxID=183763 {ECO:0000313|EMBL:KIH98456.1, ECO:0000313|Proteomes:UP000031675};
RN [1] {ECO:0000313|Proteomes:UP000031675}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 90003 {ECO:0000313|Proteomes:UP000031675};
RX PubMed=25601074; DOI=10.1016/j.chembiol.2014.11.017;
RA Metelev M., Tietz J.I., Melby J.O., Blair P.M., Zhu L., Livnat I.,
RA Severinov K., Mitchell D.A.;
RT "Structure, bioactivity, and resistance mechanism of streptomonomicin, an
RT unusual lasso Peptide from an understudied halophilic actinomycete.";
RL Chem. Biol. 22:241-250(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIH98456.1}.
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DR EMBL; JROO01000026; KIH98456.1; -; Genomic_DNA.
DR RefSeq; WP_040273815.1; NZ_JROO01000026.1.
DR AlphaFoldDB; A0A0C2JAG3; -.
DR STRING; 183763.LP52_13620; -.
DR OrthoDB; 9766690at2; -.
DR Proteomes; UP000031675; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0046942; P:carboxylic acid transport; IEA:UniProt.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR PANTHER; PTHR42865:SF7; PROTON_GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000031675};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 416..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 461 AA; 47116 MW; 712BA3385A53FBB1 CRC64;
MADEPSSPPR RSLWRRYLDF PLIYKLAIAL VAGAVVGLVV GEPATALQPL GDVFLRLLQM
LVMPLVVVTL IAGVSSVSPA RLGGIGLKVL VFYLATSAVA ITVGLLAALA VSPGTGLQAP
GQTDQSPEQA PPVTQTLLEI VPENPFAALA EGNVLAVMFA AIAAGIALAF MRSSADARIS
SLGELLRRGV DGGVELVFVI VRGVLQYAPV GVFALIAVVM AETGVDALVP LAKLTGVVYG
GVAVQIGVYV AVLALFRVGL RRFFAAAREP MVTAFATRSS SGTLPVSTRA ARRMGVDEGV
YGFTLPLGAT VNMDGTAIYV GAATVFVANV AGVELTVGQL LMVVLVGVLA SIGTAGVPGA
GLIMLSLAVT QAGLPFAPVA LVAGIDAVLD MVRTMCNVTG DLTGTRIIAR TERGMLHEPP
EDGHPPGEPE SGGDAHAVHS GAEQGHERSA GPPDTAERSG T
//
