ID   A0A0C2JC18_9ACTN        Unreviewed;       531 AA.
AC   A0A0C2JC18;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Alkaline phosphatase {ECO:0000313|EMBL:KIH98956.1};
GN   ORFNames=LP52_10825 {ECO:0000313|EMBL:KIH98956.1};
OS   Streptomonospora alba.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Nocardiopsaceae; Streptomonospora.
OX   NCBI_TaxID=183763 {ECO:0000313|EMBL:KIH98956.1, ECO:0000313|Proteomes:UP000031675};
RN   [1] {ECO:0000313|Proteomes:UP000031675}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIM 90003 {ECO:0000313|Proteomes:UP000031675};
RX   PubMed=25601074; DOI=10.1016/j.chembiol.2014.11.017;
RA   Metelev M., Tietz J.I., Melby J.O., Blair P.M., Zhu L., Livnat I.,
RA   Severinov K., Mitchell D.A.;
RT   "Structure, bioactivity, and resistance mechanism of streptomonomicin, an
RT   unusual lasso Peptide from an understudied halophilic actinomycete.";
RL   Chem. Biol. 22:241-250(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KIH98956.1}.
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DR   EMBL; JROO01000018; KIH98956.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0C2JC18; -.
DR   STRING; 183763.LP52_10825; -.
DR   OrthoDB; 327733at2; -.
DR   Proteomes; UP000031675; Unassembled WGS sequence.
DR   CDD; cd07389; MPP_PhoD; 1.
DR   Gene3D; 3.60.21.70; PhoD-like phosphatase; 1.
DR   Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   InterPro; IPR018946; PhoD-like_MPP.
DR   InterPro; IPR038607; PhoD-like_sf.
DR   InterPro; IPR032093; PhoD_N.
DR   InterPro; IPR006311; TAT_signal.
DR   PANTHER; PTHR43606; PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08710)-RELATED; 1.
DR   PANTHER; PTHR43606:SF2; PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08710)-RELATED; 1.
DR   Pfam; PF09423; PhoD; 1.
DR   Pfam; PF16655; PhoD_N; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000031675};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..40
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           41..531
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002167611"
FT   DOMAIN          53..151
FT                   /note="Phospholipase D N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16655"
FT   DOMAIN          164..499
FT                   /note="PhoD-like phosphatase metallophosphatase"
FT                   /evidence="ECO:0000259|Pfam:PF09423"
SQ   SEQUENCE   531 AA;  59346 MW;  72420F5160B0BCAB CRC64;
     MRSAASVRTR VERRRFLGIG TASAAAVALG TGLFSATASA EPADKKRDYP FTLGVASGDP
     TEDGFVLWTR LAPDPLAADG KGGMPDRPIT VEYQVALDSR FRRIVHRGSA EASPELGHSV
     HPEITGLASG REYYYRFRAM GDVSPIGTTR TAPPASSMAG SLSFAFASCQ KWDQGHYTAY
     EHMAQEDLDL VLHLGDYIYE YPIEGDLRGS VPDHLLVETT QLKHYRVRYA LYKSDVHLQN
     AHARFPWLVV PDDHEVDNNW ADEISQDDDP SAEFLQRRAD AFQAYYENMP LRRSSMPVGP
     DMGLHRRISY GRLADFTMLD TRQYRDDQAC SGRLEDDCDA RFDRNRSILG ERQRKWLLDG
     FSGSPARWQI LGNQSPMTQT DNTPGEGASV WMDPWDGYAA DRERVLDAAV QRDVRNLVVV
     TGDRHQNYAV DLKADYRDEK APTVATEFVG TSISTNGDGE DLGEQGRRFL EANPHFAFVN
     EQRGYVRCTV SPEEWRTDFR VVPYVTQQGA PVSTRASFTV ADGTPGVVQR P
//