ID A0A0C2JD09_9ACTN Unreviewed; 834 AA.
AC A0A0C2JD09;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Cell division protein FtsX {ECO:0008006|Google:ProtNLM};
GN ORFNames=LP52_22640 {ECO:0000313|EMBL:KIH96830.1};
OS Streptomonospora alba.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Streptomonospora.
OX NCBI_TaxID=183763 {ECO:0000313|EMBL:KIH96830.1, ECO:0000313|Proteomes:UP000031675};
RN [1] {ECO:0000313|Proteomes:UP000031675}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 90003 {ECO:0000313|Proteomes:UP000031675};
RX PubMed=25601074; DOI=10.1016/j.chembiol.2014.11.017;
RA Metelev M., Tietz J.I., Melby J.O., Blair P.M., Zhu L., Livnat I.,
RA Severinov K., Mitchell D.A.;
RT "Structure, bioactivity, and resistance mechanism of streptomonomicin, an
RT unusual lasso Peptide from an understudied halophilic actinomycete.";
RL Chem. Biol. 22:241-250(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family.
CC LolC/E subfamily. {ECO:0000256|ARBA:ARBA00005236}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIH96830.1}.
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DR EMBL; JROO01000047; KIH96830.1; -; Genomic_DNA.
DR RefSeq; WP_040276406.1; NZ_JROO01000047.1.
DR AlphaFoldDB; A0A0C2JD09; -.
DR STRING; 183763.LP52_22640; -.
DR OrthoDB; 9780560at2; -.
DR Proteomes; UP000031675; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR003838; ABC3_permease_dom.
DR InterPro; IPR025857; MacB_PCD.
DR PANTHER; PTHR30489; LIPOPROTEIN-RELEASING SYSTEM TRANSMEMBRANE PROTEIN LOLE; 1.
DR PANTHER; PTHR30489:SF0; LIPOPROTEIN-RELEASING SYSTEM TRANSMEMBRANE PROTEIN LOLE; 1.
DR Pfam; PF02687; FtsX; 2.
DR Pfam; PF12704; MacB_PCD; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000031675};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 255..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 349..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 483..502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 706..734
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 755..778
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 798..817
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..222
FT /note="MacB-like periplasmic core"
FT /evidence="ECO:0000259|Pfam:PF12704"
FT DOMAIN 257..376
FT /note="ABC3 transporter permease protein"
FT /evidence="ECO:0000259|Pfam:PF02687"
FT DOMAIN 483..675
FT /note="MacB-like periplasmic core"
FT /evidence="ECO:0000259|Pfam:PF12704"
FT DOMAIN 712..826
FT /note="ABC3 transporter permease protein"
FT /evidence="ECO:0000259|Pfam:PF02687"
FT REGION 107..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 834 AA; 85608 MW; D6EC83292319BFB5 CRC64;
MLRTTLAGLR MHKGRLVTTA LAIALGVMFV SGTLVFSDTL RESFSSQVMG SAERMDAVVL
PAQGSEDPVS GDVLDEVREL PEIDRAAGVT MGDAPLLDKD GRAVGSVPTA GVSVGEPTRF
SADEGELPDR PGEAALATST AEATGYEVGD SATVLGPDEQ KHEFTVTGLI DFGTEPSLAY
RGAVAFTSPV AAEMTGAEGY SEIDALAAEG VSAQQAADAV SAVAGDGTEV LTGQELGDRL
AEQAGAQADA LATGLLLFAL VSVVVAAIVI SNTFAILVAQ RQREMALLRC VGAVRRQVFT
AVVTEALVVG LLASALGVLA GVGLGYAGFA VGAEAFDADA GSADVVVKAQ TVLIGLAVGT
VTTLIAAVLP ARRATLVPPL AALRTSATAT ALDTRVGILR MATGTVLLLA SAGVVALARQ
TDDPETGLYL VVGAGFVAFA GVIVLSPLLV RAAVAAVSPL MRALGVSTAL AADNARRNPR
RAATAMIALT VGATLITGYS VVNASMMATT TDMLDRQFPM DYQVRAQFAE EGPGVPPEVA
RDLRESPEVA EVVAQRSATA ETGDGFVRYT TFRGVPPEEA AGGGTDAGDL ADVGPGRVAV
VSDVAGERGV GDTLALTTGE GERDYEIAAL VEGAQSSWSV LMDPEDFSSA FPEVRGDEML
MVSGAESAGD EELRDAVYAA VEDRPTLQVD SMAQMRRQYE DVLNTAFLAV VAMLGLAVVI
AVFGIANTLA LSVLERTRES AMLRAMGLKR AQLRVMLMWE AVLMCLVGAL VGIGLGVFFG
WAASAAVLDD LLFRVPTAQI AAFLAAAVAA GLLASVLPSR RAARTSITAA MASE
//
