ID A0A0C2M2R0_THEKT Unreviewed; 557 AA.
AC A0A0C2M2R0;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 03-MAY-2023, entry version 28.
DE SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|EMBL:KII61370.1};
GN ORFNames=RF11_12784 {ECO:0000313|EMBL:KII61370.1};
OS Thelohanellus kitauei (Myxosporean).
OC Eukaryota; Metazoa; Cnidaria; Myxozoa; Myxosporea; Bivalvulida;
OC Platysporina; Myxobolidae; Thelohanellus.
OX NCBI_TaxID=669202 {ECO:0000313|EMBL:KII61370.1, ECO:0000313|Proteomes:UP000031668};
RN [1] {ECO:0000313|EMBL:KII61370.1, ECO:0000313|Proteomes:UP000031668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wuqing {ECO:0000313|EMBL:KII61370.1};
RX PubMed=25381665; DOI=10.1093/gbe/evu247;
RA Yang Y., Xiong J., Zhou Z., Huo F., Miao W., Ran C., Liu Y., Zhang J.,
RA Feng J., Wang M., Wang M., Wang L., Yao B.;
RT "The genome of the myxosporean Thelohanellus kitauei shows adaptations to
RT nutrient acquisition within its fish host.";
RL Genome Biol. Evol. 6:3182-3198(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KII61370.1}.
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DR EMBL; JWZT01005339; KII61370.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C2M2R0; -.
DR EnsemblMetazoa; KII61370; KII61370; RF11_12784.
DR Proteomes; UP000031668; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007420; P:brain development; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR047161; GIT-like.
DR PANTHER; PTHR46097:SF3; ARF GTPASE-ACTIVATING PROTEIN GIT; 1.
DR PANTHER; PTHR46097; G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP; 1.
DR Pfam; PF01412; ArfGap; 1.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000031668};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 1..121
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 397..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..440
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 557 AA; 64106 MW; B5E7862D12E725B5 CRC64;
MDYKNLPCSD CGYEGCNWLS LNNFVILCDR CVVVHFNLGS MISQIYHINH LSCVPSIFSK
LFDDMWTRSA HALWVQNLKN FLELNPSRSR IYPQSNKNER KEFIQLKYKQ RTFLTPMSNS
FEADIVIKNT IKNGDQIGLF RSIINNADLE AKDPNGQSLI HIAVKDENKH ALAMLYLWGA
NIYENNSFME SAIDIAVEAK NTSMISALIE IIMEIPDMFT LYLAGYKPDH EMDVHLVLPN
LSKLGFNQDL PCVEMSKFLK KVHFILFLIS SEDFTDLSSD IYEECVRRLC EAENKKCNGI
PEAFRILPMC TLVPDPRNKF RASLSKYDGP RFALLLYHLL YEISQFKGTN AINEVDFKEK
IDEQPIIRYN IQRKDIWREE PKYESSSNPL ESYLHQKTST DVPKKQATPT PIIHGKPPPI
LDKQENHESK SSSTPKINEK EKFNRWKQGF DDVVDKLFRI IELTQRSVKV QNGSGVKKGI
VDSATNVKSL ITFCQNCSII ELKSELKFLE LVSFVKRLNE VNNGPDEAHK KFATLTDILN
EFKSALDVLN DRVQKFS
//
