ID A0A0C3CBF4_HEBCY Unreviewed; 1127 AA.
AC A0A0C3CBF4;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN ORFNames=M413DRAFT_16853 {ECO:0000313|EMBL:KIM46105.1};
OS Hebeloma cylindrosporum h7.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hymenogastraceae; Hebeloma.
OX NCBI_TaxID=686832 {ECO:0000313|EMBL:KIM46105.1, ECO:0000313|Proteomes:UP000053424};
RN [1] {ECO:0000313|EMBL:KIM46105.1, ECO:0000313|Proteomes:UP000053424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=h7 {ECO:0000313|Proteomes:UP000053424};
RG DOE Joint Genome Institute;
RA Kuo A., Gay G., Dore J., Kohler A., Nagy L.G., Floudas D., Copeland A.,
RA Barry K.W., Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A.,
RA Lipzen A., Lundell T., Morin E., Murat C., Sun H., Tunlid A., Henrissat B.,
RA Grigoriev I.V., Hibbett D.S., Martin F., Nordberg H.P., Cantor M.N.,
RA Hua S.X.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=h7 {ECO:0000313|Proteomes:UP000053424};
RG DOE Joint Genome Institute;
RG Mycorrhizal Genomics Consortium;
RA Kohler A., Kuo A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Riley R., Ohm R., Sun H., Tunlid A.,
RA Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.;
RT "Evolutionary Origins and Diversification of the Mycorrhizal Mutualists.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC ECO:0000256|RuleBase:RU363098};
CC -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC ECO:0000256|RuleBase:RU363098}.
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DR EMBL; KN831771; KIM46105.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C3CBF4; -.
DR STRING; 686832.A0A0C3CBF4; -.
DR HOGENOM; CLU_003387_1_0_1; -.
DR OrthoDB; 2735303at2759; -.
DR Proteomes; UP000053424; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR PANTHER; PTHR23079:SF14; RNA-DEPENDENT RNA POLYMERASE; 1.
DR Pfam; PF05183; RdRP; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW Reference proteome {ECO:0000313|Proteomes:UP000053424};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000256|RuleBase:RU363098};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
FT REGION 42..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 891..919
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..104
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 891..914
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1127 AA; 128789 MW; AE11457B8B5BDCEB CRC64;
MSFVDRVEKG RICFLAERTA SEHTSYSNFG DDDISPLIRL FNPTQSSEDD KPPDSATSSE
TSLGKRKSSD ISSSSTIASG PFRPPKIARS IPQCEEDKSP ENPFIDHGPL EPEIPESPFT
PIILSPGKAL QAQFTARKLP YGVQYEIARY VTIGKLQYNQ LYIPCLDNFA ALKTNREAVP
ATAKIVLSDP CDASEETEGN QDQWDNLFAK ERAAKSPWEE LDREEESLSK SPYGGLGFDE
EGEHIGWHGG KILFHGKLQD ASAKGCKKPP KYKITLDRAE LSTSNMFARR FGSKHFFRLK
LTKPILNRNT DLLMNYIRRP LILCGNVFRA FYAKDTNVFY VKTNERTDGS IILRGETIPG
VMSFLEFLDW HNPMALNTEQ TMAKYVSRFA LGLSNSFPGL LMEQSNIKFI DDIISETGSN
MTDGAGKINR WALKQIRHRL NWEDQPTAIQ TRIFGTKGLL VEDGKNPEEY AVVEITPSQR
KIRLQENTAI DPAHRIIDVL RASHTKTPCR LSVETIINLA HNGVTKRVFL ELLQKGLADL
VEPLLDWDSP DAMRKLWSNV RRLGGVMAAR RAREEAGLAR VKGFSEREAE EIEIDDEEDF
NSAELAEQRS SAWWGDEVSG CPSSLEETIM YMIDSGLTPK ECPLLRDKLD KFIRSRLTNY
IKSYRIDVPM SASAFLVPDT SGILEEGQVF YKSSRREFLT PEGFKTDVYV GDVLLTRIPC
KLPTDMQKWK SVDIPELHHL TDVIVFSTKG NRRAADFLSG GDYDGDKGIY IWQPELVEAF
NNAPLHFSEP PADIKKYFAR ENEEVATFQK KIATISEENK IHQLQKWLLG AVRDTTVVGK
YSTFHEISTY LYGYDHPDTI RLAYMFCMVL DGIKTGMTVR SDVLKQDTAR FQKRPPRWKE
TEEERERNEQ TNEPNIKRPQ ELGKFIMDEL LKQAEVEGKR WLARLDDEFK VGGLCKLDKD
LAAPWYAALE LGERWQAEES NGRFLADLDS LRRHIADLYN EYRTEMNSPR KQSRMSPSKK
DKPFTSLPIE VRQDKIRKLS KQFASYPRSG HFLMLDEDVA RVRASCAYVY DYEQRKSYSS
NNYSRFPWDL AMRELCAIKA RANGRPKTVD GDFYDHFNMK HPKTHHF
//
