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Database: UniProt
Entry: A0A0C3I5Z6_9VIBR
LinkDB: A0A0C3I5Z6_9VIBR
Original site: A0A0C3I5Z6_9VIBR 
ID   A0A0C3I5Z6_9VIBR        Unreviewed;       902 AA.
AC   A0A0C3I5Z6;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   08-MAY-2019, entry version 39.
DE   RecName: Full=HTH-type transcriptional regulator MalT {ECO:0000256|HAMAP-Rule:MF_01247, ECO:0000256|SAAS:SAAS00724615};
DE   AltName: Full=ATP-dependent transcriptional activator MalT {ECO:0000256|HAMAP-Rule:MF_01247};
GN   Name=malT {ECO:0000256|HAMAP-Rule:MF_01247};
GN   ORFNames=SU60_12510 {ECO:0000313|EMBL:KIN10450.1};
OS   Vibrio mytili.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Vibrio.
OX   NCBI_TaxID=50718 {ECO:0000313|EMBL:KIN10450.1};
RN   [1] {ECO:0000313|EMBL:KIN10450.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CAIM 528 {ECO:0000313|EMBL:KIN10450.1};
RA   Gonzalez-Castillo A., Gomez-Gil B., Enciso-Ibarra J.;
RT   "Draft genome of Vibrio mytili type strain CAIM 528.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Positively regulates the transcription of the maltose
CC       regulon whose gene products are responsible for uptake and
CC       catabolism of malto-oligosaccharides. Specifically binds to the
CC       promoter region of its target genes, recognizing a short DNA motif
CC       called the MalT box. {ECO:0000256|HAMAP-Rule:MF_01247}.
CC   -!- ACTIVITY REGULATION: Activated by ATP and maltotriose, which are
CC       both required for DNA binding. {ECO:0000256|HAMAP-Rule:MF_01247,
CC       ECO:0000256|SAAS:SAAS01071122}.
CC   -!- SUBUNIT: Monomer in solution. Oligomerizes to an active state in
CC       the presence of the positive effectors ATP and maltotriose.
CC       {ECO:0000256|HAMAP-Rule:MF_01247}.
CC   -!- SIMILARITY: Belongs to the MalT family. {ECO:0000256|HAMAP-
CC       Rule:MF_01247, ECO:0000256|SAAS:SAAS01044130}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KIN10450.1}.
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DR   EMBL; JXOK01000049; KIN10450.1; -; Genomic_DNA.
DR   RefSeq; WP_041155794.1; NZ_JXOK01000049.1.
DR   EnsemblBacteria; KIN10450; KIN10450; SU60_12510.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0045913; P:positive regulation of carbohydrate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.25.40.10; -; 1.
DR   HAMAP; MF_01247; HTH_type_MalT; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR041617; TPR_MalT.
DR   InterPro; IPR023768; Tscrpt_reg_HTH_MalT.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF00196; GerE; 1.
DR   Pfam; PF17874; TPR_MalT; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|HAMAP-Rule:MF_01247,
KW   ECO:0000256|SAAS:SAAS00724627};
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_01247,
KW   ECO:0000256|SAAS:SAAS00724618};
KW   Carbohydrate metabolism {ECO:0000256|HAMAP-Rule:MF_01247,
KW   ECO:0000256|SAAS:SAAS00724617}; Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_01247,
KW   ECO:0000256|SAAS:SAAS01008967};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01247,
KW   ECO:0000256|SAAS:SAAS00724612};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_01247,
KW   ECO:0000256|SAAS:SAAS00053185};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_01247,
KW   ECO:0000256|SAAS:SAAS00053955}.
FT   DOMAIN      832    897       HTH luxR-type. {ECO:0000259|PROSITE:
FT                                PS50043}.
FT   NP_BIND      39     46       ATP. {ECO:0000256|HAMAP-Rule:MF_01247}.
FT   COILED      418    438       {ECO:0000256|SAM:Coils}.
FT   COILED      736    756       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   902 AA;  104077 MW;  FB659C8F705CD0AC CRC64;
     MWIPSKLTRP GRLHNAIVRP RVLDLLQQAP CYKLVLFRSP AGYGKTTMAA QWLSDKPNVG
     WYSIDDSDND DFRFVNYLLQ ALNKATHSSC SNAQKLAEKR QISSLRSLFS EVFAEMADFH
     QECYVVLDDY HLITNDEIHE SMRFFLKHMP DNLTVVVTSR AAPPLGTANL RVRDLMIEVG
     NEMLAFDTEE TTRFFNQRVA DGIDEDMAND LRAYVEGWPS AMQLIALQAQ HQKRTLAQTV
     ESVSQFNHAH LWDYLVEEVF DLLDNETRQF LMQVSVLDHF NDELVFALTQ REDALGLIES
     LNRYGLFIYP LDGEQNWFRF HNLFGEFLSH QRQARIPQQE KELHRNAAIA WLQQESPHQA
     IHHAQKSDDK HLVVDILNQY GWKMFNQGEL STLEIAINKL DADLLYFHPK LTMLRAWLAQ
     SQHRYNQVGQ LLKEAEEEHK KRDIELDIHY QGQANALLAQ VAINNNEPEK ALELAELALS
     QLDHTIYRSR IVATSVVGEV NHVLGKLDRA LPMMQQTEKL ARQYQVYHQA LWAILQQSEI
     LIAQGYVQAA FEVQDSGFRL IEEHQLQHVP LHEFLLRIRA QVLWCWNRLD EAEECSYKGL
     QILENHSPSK HLHSYSMLAR IAVGRGELDK AGKFIEHIQH LMRQSTYHVD WTANASLSLI
     LFWQARGDTE AMQEWLNTAV RPESACNHFL QLQWRNITRA HINLGQFEQA RQTLDFLQSE
     ASKSHLVTDT NRNLVVEAAL AARQKDEEQA KRLLKEALVM TNQTGMVGNF LVDGATIGGL
     LEKLSLRHEL GDLERHRAQQ LMKDISSNQR SRSVHFDEDF IEKLVNHPNV PELVRTSPLT
     QREWQVLGLI YSGFSNEQIA QELDVAGTTI KTHIRNLYQK LNIANRKEAI ITAENLLQLM
     GY
//
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