ID A0A0C3PVP4_PISTI Unreviewed; 854 AA.
AC A0A0C3PVP4;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Beta-mannosidase B {ECO:0000256|ARBA:ARBA00041069};
DE EC=3.2.1.25 {ECO:0000256|ARBA:ARBA00012754};
DE AltName: Full=Mannanase B {ECO:0000256|ARBA:ARBA00041614};
GN ORFNames=M404DRAFT_13043 {ECO:0000313|EMBL:KIO12929.1};
OS Pisolithus tinctorius Marx 270.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Boletales; Sclerodermatineae; Pisolithaceae; Pisolithus.
OX NCBI_TaxID=870435 {ECO:0000313|EMBL:KIO12929.1, ECO:0000313|Proteomes:UP000054217};
RN [1] {ECO:0000313|EMBL:KIO12929.1, ECO:0000313|Proteomes:UP000054217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Marx 270 {ECO:0000313|EMBL:KIO12929.1,
RC ECO:0000313|Proteomes:UP000054217};
RG DOE Joint Genome Institute;
RA Kuo A., Kohler A., Costa M.D., Nagy L.G., Floudas D., Copeland A.,
RA Barry K.W., Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A.,
RA Lipzen A., Lundell T., Morin E., Murat C., Sun H., Tunlid A., Henrissat B.,
RA Grigoriev I.V., Hibbett D.S., Martin F., Nordberg H.P., Cantor M.N.,
RA Hua S.X.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Marx 270 {ECO:0000313|Proteomes:UP000054217};
RG DOE Joint Genome Institute;
RG Mycorrhizal Genomics Consortium;
RA Kohler A., Kuo A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Riley R., Ohm R., Sun H., Tunlid A.,
RA Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.;
RT "Evolutionary Origins and Diversification of the Mycorrhizal Mutualists.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-mannose residues
CC in beta-D-mannosides.; EC=3.2.1.25;
CC Evidence={ECO:0000256|ARBA:ARBA00000829};
CC -!- PATHWAY: Glycan metabolism; N-glycan degradation.
CC {ECO:0000256|ARBA:ARBA00004740}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family. Beta-
CC mannosidase B subfamily. {ECO:0000256|ARBA:ARBA00038429}.
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DR EMBL; KN831947; KIO12929.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C3PVP4; -.
DR STRING; 870435.A0A0C3PVP4; -.
DR HOGENOM; CLU_005015_1_1_1; -.
DR InParanoid; A0A0C3PVP4; -.
DR OrthoDB; 2504097at2759; -.
DR Proteomes; UP000054217; Unassembled WGS sequence.
DR GO; GO:0004567; F:beta-mannosidase activity; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR041447; Mannosidase_ig.
DR PANTHER; PTHR43730; BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR43730:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF17786; Mannosidase_ig; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 2.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KIO12929.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054217}.
FT DOMAIN 195..301
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 682..774
FT /note="Mannosidase Ig/CBM-like"
FT /evidence="ECO:0000259|Pfam:PF17786"
SQ SEQUENCE 854 AA; 97092 MW; 3332BA894EFC46ED CRC64;
MSAIKFLHSD WVFTQVGGGQ GTRCGEWLPV TEFPTTVHVE LLKLKRIPDP FLGMNEWEVQ
WVGESDWTFK NNFTITNAEL AACHVDLIFE GLDTYATVTL NDREILGTAD QFVTHRVSAK
QHLQPGSNEL AITFTSAFRK GRELEKEYGK FHLWNGDSSR LHVRKAQYNY GWDWGPVLMT
IGPWKPIFLH TYDLRIADVD IRCRVAEALD VDITVDLALS KDSPGSASVL LRDPHGSVAR
YQDALAVETG RASTKFYFSS GEAELWYPVH YGKQPLYTIE VVVKGVDGRV MDSRHEKVAF
RRAQVLEEPL IDQPGKTFLF EINNIRIFCA GSNWIPADSF LTLLSPQRYR DWLRLVVDGN
QNMVRVWGGG IYEADIFYDI CDVLVWQDFM FGCGQYPAYD SFLKLVEVEA RQNVKRLRNH
PSVVILAGNN EDYQLAESLN LIEYSGETSE CSETKFPARR IYESLLPSIV SELCDIHYHK
GSPYSAPGVP TTDPTLGDLH QWNVWHGSQQ PWQNWDTLSG RFVSEFGMQG YPNVRTIDHW
LNGRTDERFP QSRFNNQHNK AAGFEGRLEL YLVENFRHTF DMDSYVYYTQ IMQAEALATA
YRLWRRNWRG KGREYTAGAL VWQMNDCWPT TSWAIVDYFL RPKPAYFAIS RELAPFAVGI
TRKEKKTFTN ELSASSFIIE TILEVWGTNS TVAEKKARLE LTFFELDTNW SDKISMEVVM
APNSSTELFS DQLSGQPIRT KLSEVPRTII VSARLLDEAG VVLGRLSNWP EPYKFIHFPS
VKDLGLSITI GSDGESVELA ARVPVKGIVL DVEGNDVKWS DQAIDLFPGD PQIVKAVGLG
GREVKVRFLG DSSS
//
