ID A0A0C3QGQ5_9AGAM Unreviewed; 1808 AA.
AC A0A0C3QGQ5;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Actin cytoskeleton-regulatory complex protein PAN1 {ECO:0000256|ARBA:ARBA00015110};
DE AltName: Full=Actin cytoskeleton-regulatory complex protein pan1 {ECO:0000256|ARBA:ARBA00020728};
GN ORFNames=M407DRAFT_15224 {ECO:0000313|EMBL:KIO25586.1};
OS Tulasnella calospora MUT 4182.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Tulasnellaceae; Tulasnella.
OX NCBI_TaxID=1051891 {ECO:0000313|EMBL:KIO25586.1, ECO:0000313|Proteomes:UP000054248};
RN [1] {ECO:0000313|EMBL:KIO25586.1, ECO:0000313|Proteomes:UP000054248}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUT 4182 {ECO:0000313|EMBL:KIO25586.1,
RC ECO:0000313|Proteomes:UP000054248};
RG DOE Joint Genome Institute;
RA Kuo A., Girlanda M., Perotto S., Kohler A., Nagy L.G., Floudas D.,
RA Copeland A., Barry K.W., Cichocki N., Veneault-Fourrey C., LaButti K.,
RA Lindquist E.A., Lipzen A., Lundell T., Morin E., Murat C., Sun H.,
RA Tunlid A., Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.,
RA Nordberg H.P., Cantor M.N., Hua S.X.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054248}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUT 4182 {ECO:0000313|Proteomes:UP000054248};
RG DOE Joint Genome Institute;
RG Mycorrhizal Genomics Consortium;
RA Kohler A., Kuo A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Riley R., Ohm R., Sun H., Tunlid A.,
RA Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.;
RT "Evolutionary Origins and Diversification of the Mycorrhizal Mutualists.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; KN823039; KIO25586.1; -; Genomic_DNA.
DR STRING; 1051891.A0A0C3QGQ5; -.
DR HOGENOM; CLU_235129_0_0_1; -.
DR OrthoDB; 2734911at2759; -.
DR Proteomes; UP000054248; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd00052; EH; 1.
DR CDD; cd00160; RhoGEF; 1.
DR CDD; cd00174; SH3; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR000261; EH_dom.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR46006:SF5; DH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46006; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A; 1.
DR Pfam; PF12763; EF-hand_4; 1.
DR Pfam; PF16652; PH_13; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF02205; WH2; 1.
DR SMART; SM00027; EH; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS50031; EH; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS51082; WH2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000054248};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 104..193
FT /note="EH"
FT /evidence="ECO:0000259|PROSITE:PS50031"
FT DOMAIN 137..172
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 989..1006
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT DOMAIN 1184..1243
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1475..1656
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 1693..1787
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 208..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 359..991
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1248..1270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1287..1344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1421..1446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..225
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..282
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..450
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 465..492
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..582
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..678
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 689..732
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 747..774
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..806
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 807..822
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 823..866
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 872..904
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 936..980
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1297..1311
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1326..1344
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1808 AA; 196671 MW; B19EF9A5DAC289E3 CRC64;
MGGLAPQPTG LLPQQTGWGG SAAGGAGLSP LVAQPTGFGD PRMSMMSQTF MPANTSMPYG
PGSTPQFAGP PQQAQGLSLQ QSIQQHNQAV GGGPKISWAL SKDERKSYDN IFRAWDAQGA
GFISGKAVLE VFGQSGLSQD DLSKIWDLAD STNRGSLNLA EFHVAMGIIY RALNGAPIPN
VLPPELVPPS ERDLGDSVNF LKDILSKDSH ERASNGSSPN PQYGKIRSLH GTPAGDPLRG
GRKDGAAYVH DDSDTRGYKS SSRHLDRRAV RYGGESPASD LDEMKRQLQS ASSQLDSRIE
AENARTREDE ELEDELNELK YRVKRVQEDL DRTNRGPRSV RKDEERRRLE RELLQLLHEK
IPEVERKLED REREKQKERD GWRRERDRRN ADSSRYGRDR SDRYDSYDNS RDEEDRGYLR
GTYDDRDGYD RHRDRGERER DSDRDRSYSS YPRTRSPPAS TRSPPPRSSS ALGGSTRSPP
PTSSTLSSAS VPAVPHSPAK MTPAEKAAFV KAEAQRRMQE RMRALGVSPS PAAASTASPG
APEVDSSVEE RLARERKEAQ EKAEKAEREA EERERARRAR VQEAKGILSA PASTIEPTVS
VPASAPEVAR SPPAPPVPSA QAIPRAKPAP PPPVKPRAPA PPPPVRGGAR VAPQPPKPPI
AAPTPPAPVF APPPIAPVPN EEDDEDAKME AELARLREAA KARANEQRLA RRRELERQLE
EARREEESHQ VKASTSSNDP KDTIPTPVQA PTSPPRAPLA PSQAPAPTVP SVPPAGSTNP
FHKFAKPAPQ STPTAPVPPP PKTTPSAGTG TNPFFNRQAS QSQPPAPPAP VLPPLQTAPP
VPPAPPAPVL AAPRTIPRPS STPIPVPKTK LPQADDTDED WDSPKEKDND SDSSDEDFVD
RAAMNKIADR IFGTGGAPPR PQSAAPALAQ QQAAGMAPPA PPPPMTAPPT AAPQLPFVAP
APPPPPMVPP PPPPAPALPA PTASSGSGDR GALFAAIQGG KALRKAVTND RSGAGLSGRV
IGDAAPPAHI SEVPREASPP VAFVPEAAPA SQPLGSQVSS KSDNRQSVDW FAGLAADGGV
VGKPSQSIQA MESHAEENEE AVPHITIHDH DTKSDDLVDV DLTKEHRTRT LYAYEAQRAE
EISFGENQVI LAHPSKSGDV WWYGSLVRGG PKGFFPNTYV QVIDQVVQAK AMYAYSATNQ
EEMSFNAGDT LDIIDRSEAD WWKTEKEGSI LMVPASYLEL HEDSEEYLSV ASDEGNGKAT
SSTVTDRKAE AEVRALERQR VLEAAGLIIK PADASAPPRP PRKHRPPPKV PERSSRATPD
TLSRSQVERD LPEIPKGEEP AMRLEDAYDR YEAFRRRQQE PPPSGNRLSI VSTSSLESSP
MVSSPTGTVF SVQAPSLAQS TSSSTGETAR HGASAFLHSF LGRRTPGPEK NRLTISAPIP
SGGEIPRTPS PAFGTSWSSL VDKDVLEGIP PAERKRQEAI FELIVTESAY VRDLQLIVEV
FYTSLIDVLD QKATTVIFAN VEDILLCNTS FYSALEERQK DCRLYMDQLG DLLQVHMGNM
AVYTPYCVNQ SIATKILQTI RASNPDVASR LQRLKDDPVC RNLDLSSYLL IPMQRITRYP
LLLRQILNYT QSETERKQLE WAIATTERIL DSINETIREN EGAERLAEVS RDLYIGEGRL
DLTARTKYLG KRKLVKEGEV TKAKSGRKLH LILCNDVLVL LDAAARSLYR MPIPLSELKI
REAPGGKNDL GFQLALAYPR GGDIISVKAT SARDCHQWMQ AISQASEYCK SVEQRAERRK
SRSSGIGY
//
