ID A0A0C3QU44_9AGAM Unreviewed; 259 AA.
AC A0A0C3QU44;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Protein AF-9 homolog {ECO:0000256|ARBA:ARBA00022408, ECO:0000256|RuleBase:RU367117};
GN Name=YAF9 {ECO:0000256|RuleBase:RU367117};
GN ORFNames=M407DRAFT_96331 {ECO:0000313|EMBL:KIO32841.1};
OS Tulasnella calospora MUT 4182.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Tulasnellaceae; Tulasnella.
OX NCBI_TaxID=1051891 {ECO:0000313|EMBL:KIO32841.1, ECO:0000313|Proteomes:UP000054248};
RN [1] {ECO:0000313|EMBL:KIO32841.1, ECO:0000313|Proteomes:UP000054248}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUT 4182 {ECO:0000313|EMBL:KIO32841.1,
RC ECO:0000313|Proteomes:UP000054248};
RG DOE Joint Genome Institute;
RA Kuo A., Girlanda M., Perotto S., Kohler A., Nagy L.G., Floudas D.,
RA Copeland A., Barry K.W., Cichocki N., Veneault-Fourrey C., LaButti K.,
RA Lindquist E.A., Lipzen A., Lundell T., Morin E., Murat C., Sun H.,
RA Tunlid A., Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.,
RA Nordberg H.P., Cantor M.N., Hua S.X.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054248}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUT 4182 {ECO:0000313|Proteomes:UP000054248};
RG DOE Joint Genome Institute;
RG Mycorrhizal Genomics Consortium;
RA Kohler A., Kuo A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Riley R., Ohm R., Sun H., Tunlid A.,
RA Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.;
RT "Evolutionary Origins and Diversification of the Mycorrhizal Mutualists.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the SWR1 complex which mediates the ATP-
CC dependent exchange of histone H2A for an H2A variant leading to
CC transcriptional regulation of selected genes by chromatin remodeling.
CC Component of the NuA4 histone acetyltransferase complex which is
CC involved in transcriptional activation of selected genes principally by
CC acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is
CC also involved in DNA repair. Yaf9 may also be required for viability in
CC conditions in which the structural integrity of the spindle is
CC compromised. {ECO:0000256|RuleBase:RU367117}.
CC -!- FUNCTION: Component of the SWR1 complex which mediates the ATP-
CC dependent exchange of histone H2A for the H2A variant HZT1 leading to
CC transcriptional regulation of selected genes by chromatin remodeling.
CC Component of the NuA4 histone acetyltransferase complex which is
CC involved in transcriptional activation of selected genes principally by
CC acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is
CC also involved in DNA repair. Yaf9 may also be required for viability in
CC conditions in which the structural integrity of the spindle is
CC compromised. {ECO:0000256|ARBA:ARBA00025636}.
CC -!- SUBUNIT: Component of the SWR1 chromatin-remodeling complex and of the
CC NuA4 histone acetyltransferase complex. {ECO:0000256|ARBA:ARBA00038745,
CC ECO:0000256|RuleBase:RU367117}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU367117}.
CC Cytoplasm {ECO:0000256|RuleBase:RU367117}.
CC -!- DOMAIN: The coiled-coil domain is required for assembly into the NuA4
CC complex. {ECO:0000256|RuleBase:RU367117}.
CC -!- SIMILARITY: Belongs to the YAF9 family. {ECO:0000256|ARBA:ARBA00038419,
CC ECO:0000256|RuleBase:RU367117}.
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DR EMBL; KN822952; KIO32841.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C3QU44; -.
DR STRING; 1051891.A0A0C3QU44; -.
DR HOGENOM; CLU_051385_2_1_1; -.
DR OrthoDB; 128693at2759; -.
DR Proteomes; UP000054248; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0035267; C:NuA4 histone acetyltransferase complex; IEA:UniProtKB-UniRule.
DR GO; GO:0000812; C:Swr1 complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16908; YEATS_Yaf9_like; 1.
DR Gene3D; 2.60.40.1970; YEATS domain; 1.
DR InterPro; IPR038704; YEAST_sf.
DR InterPro; IPR005033; YEATS.
DR PANTHER; PTHR23195; YEATS DOMAIN; 1.
DR PANTHER; PTHR23195:SF15; YEATS DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF03366; YEATS; 1.
DR PROSITE; PS51037; YEATS; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159, ECO:0000256|RuleBase:RU367117};
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853,
KW ECO:0000256|RuleBase:RU367117};
KW Coiled coil {ECO:0000256|RuleBase:RU367117};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|RuleBase:RU367117};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU367117};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU367117};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00376}; Reference proteome {ECO:0000313|Proteomes:UP000054248};
KW Transcription {ECO:0000256|RuleBase:RU367117};
KW Transcription regulation {ECO:0000256|RuleBase:RU367117}.
FT COILED 221..259
FT /evidence="ECO:0000256|RuleBase:RU367117"
SQ SEQUENCE 259 AA; 29280 MW; 2A520B3D7C597BAC CRC64;
MAERSERLRG TVIYRPVVYG NTALPITPET RDDAPAEHTH RWTVALRSAA SPDDGSTVGG
RDDISYFVKR VAFKLHETYP SPNRIIEKPP FEVTETGWGE FEVQIRVTFV SEANEKPISF
HHHLKLHAWA PQPANPLAAS PVPTPPDGPV NAWQYDEIVF TDPTKTFLDM LLKHPPTPLP
KNRRRGAPPH VAYPASLVNQ AKGGGMPEFT QLMEKEEAER LDQAKKDIVA ETDKLRNLLI
EREKELERLK KEVEGMQRS
//
